Exercise program for children and young adults with cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the physical and emotional benefits of a structured exercise regimen for pediatric patients aged 2-25 who are newly diagnosed with blood or solid tumor cancers and undergoing treatment. Participants will be randomly assigned to either the exercise intervention group or a control group receiving standard care. The effectiveness of the exercise program will be measured using the 6-Minute Walk test and other assessments to evaluate physical functioning. The goal is to determine if exercise can help maintain or improve physical capabilities during cancer treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Ages 2-25 at time of consent
2. Subject has newly diagnosed cancer per Investigator, and is planning to undergo chemotherapy for treatment of malignancy for at least 3 full cycles
3. Ability of subject (and/or parent/guardian) to read and understand the English or Spanish language
4. As determined and documented by the enrolling investigator, ability of the subject to understand and comply with study procedures for the entire length of the study
5. Subject has newly diagnosed cancer per Investigator and is planning to undergo chemotherapy, immunotherapy, or other systemically delivered for treatment of malignancy. Subjects are allowed to be enrolled up to 21 days after initiating cancer treatment.
6. Receiving oncologic care at Levine Children's Cancer and Blood Disorders Clinic.
7. Subject is anticipated to receive at least 3 full cycles of chemotherapy or other systemic cancer treatment.
8. Not participating in another clinical trial that precludes participating in additional nondrug clinical trials.

Exclusion Criteria:

1. Known cardiac dysfunction that, in the opinion of the investigator, would be unsafe for the child to participate in the exercise program
2. Any other uncontrolled intercurrent illness/medical condition or psychiatric illness/social situations that would limit compliance with study requirements or would be considered unsafe for the child to participate as determined by the Investigator.
3. Recent (within 4 weeks of enrollment) or planned surgery that will result in prolonged limited mobility not amendable to exercise modifications per investigator discretion
4. Primary CNS Tumor
5. Osteosarcoma

Where it's running

• Levine Children's Hospital
  Charlotte, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Jennifer Pope, MD — Wake Forest University Health Sciences
• Study coordinator: Meg Lattanze
• Email: Megan.Lattanze@advocatehealth.org
• Phone: (980) 442-4239

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.