Exercise program for adults with mild to moderate cognitive impairments
Official title: Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments
Run by University of South Carolina · NCT06799429 · Data updated 2026-11-12
This study tests a 6-month exercise program for adults with mild to moderate cognitive impairments to see if it helps them feel better and improve their physical and mental abilities.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | University of South Carolina Academic / other |
| Locations | 2 sites (Columbia, South Carolina and 1 other locations) |
| Status | Recruiting |
| Started | March 13, 2026 |
| Main results expected | October 31, 2026 |
| Study ends | November 17, 2026 |
| Registry record updated | June 1, 2026 |
| Trial ID | NCT06799429 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults diagnosed with mild to moderate cognitive impairment who are medically cleared for exercise.
✕Probably not a fit
Patients with significant pain during movement or severe balance impairments may not benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates a 6-month exercise program designed for adults with mild to moderate cognitive impairments in South Carolina. Participants will engage in moderate intensity exercise twice a week, either in-person with a coach or through a distance program with coaching support. The study aims to assess the practicality and enjoyment of the program, as well as its effects on endurance, mobility, and cognitive function over time. Participants will receive individualized exercise plans based on their initial assessments and will be monitored for progress.
Why it matters
Potential benefit: If successful, this program could improve physical fitness and cognitive function in individuals with cognitive impairments.
How similar studies have gone: Other studies have shown positive outcomes with exercise interventions for cognitive impairments, suggesting this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * adult (age \>18) * medical diagnosis of mild-moderate cognitive impairment * medical clearance by referring provider for exercise * able to follow 2-step commands Exclusion criteria: * significant pain with movement (\>5/10) * severe balance impairments or lack of independence on and off exercise equipment (by physical therapist judgment at Intake)
Where it's running
-
Arnold School of Public Health
Columbia, South Carolina, United States Recruiting -
Sumter YMCA
Sumter, South Carolina, United States Recruiting
Study contacts
- Study coordinator: Elizabeth Regan, PhD
- Email: eregan@mailbox.sc.edu
- Phone: 7046092409
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.