Exercise program for adults with mild to moderate cognitive impairments

Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments

Not applicable Interventional University of South Carolina · NCT06799429

This study tests a 6-month exercise program for adults with mild to moderate cognitive impairments to see if it helps them feel better and improve their physical and mental abilities.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of South Carolina Academic / other
Locations2 sites (Columbia, South Carolina and 1 other locations)
Trial IDNCT06799429 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates a 6-month exercise program designed for adults with mild to moderate cognitive impairments in South Carolina. Participants will engage in moderate intensity exercise twice a week, either in-person with a coach or through a distance program with coaching support. The study aims to assess the practicality and enjoyment of the program, as well as its effects on endurance, mobility, and cognitive function over time. Participants will receive individualized exercise plans based on their initial assessments and will be monitored for progress.

Who should consider this trial

Good fit: Ideal candidates are adults diagnosed with mild to moderate cognitive impairment who are medically cleared for exercise.

Not a fit: Patients with significant pain during movement or severe balance impairments may not benefit from this program.

Why it matters

Potential benefit: If successful, this program could improve physical fitness and cognitive function in individuals with cognitive impairments.

How similar studies have performed: Other studies have shown positive outcomes with exercise interventions for cognitive impairments, suggesting this approach is promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

* adult (age \>18)
* medical diagnosis of mild-moderate cognitive impairment
* medical clearance by referring provider for exercise
* able to follow 2-step commands

Exclusion criteria:

* significant pain with movement (\>5/10)
* severe balance impairments or lack of independence on and off exercise equipment (by physical therapist judgment at Intake)

Where this trial is running

Columbia, South Carolina and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mild-moderate Cognitive Impairmentcognitive impairmentexercise
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.