Exercise interventions for cancer survivors with nerve damage from chemotherapy
The Effects of Remote Exercise Program in Patients With Digestive Tract Cancer and Chemotherapy-induced Peripheral Neuropathy
This study tests whether different types of exercise can help cancer survivors with nerve damage from chemotherapy feel better and improve their quality of life.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 20 Years to 80 Years |
| Sex | All |
| Sponsor | National Cheng-Kung University Hospital Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Tainan) |
| Trial ID | NCT06331962 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of exercise on chemotherapy-induced peripheral neuropathy (CIPN) in survivors of digestive tract cancer. Participants will be assigned to one of three groups: remote home-based exercise therapy, supervised exercise therapy, or regular care. The study aims to assess improvements in CIPN symptoms, body inflammatory index, physical function, and quality of life at various time points. By exploring different modes of exercise delivery, the research seeks to establish effective guidelines for managing CIPN in cancer survivors.
Who should consider this trial
Good fit: Ideal candidates are adults aged 20 and above who have been diagnosed with gastrointestinal cancer and are experiencing chemotherapy-induced peripheral neuropathy.
Not a fit: Patients with cognitive impairments, significant neurological or cardiovascular issues, or those aged 80 and above may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide effective exercise guidelines to alleviate CIPN symptoms and improve the quality of life for cancer survivors.
How similar studies have performed: While there is limited research on exercise interventions specifically for CIPN in digestive tract cancer patients, similar studies have shown positive outcomes in other cancer populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 20 and above; 2. Diagnosed by a physician with gastrointestinal cancer and has undergone chemotherapy or is currently undergoing chemotherapy; 3. Diagnosed by a physician with chemotherapy-induced peripheral neuropathy. Exclusion Criteria: 1. Cognitive impairment or inability to cooperate with verbal instructions; 2. Neurological, muscular, skeletal, or cardiovascular issues preventing participation in exercise training; 3. Age 80 or above; 4. Refusal to engage in exercise intervention or participate in data collection.
Where this trial is running
Tainan
- Department of Physical Therapy, National Cheng-Kung University — Tainan, Taiwan (Recruiting)
Study contacts
- Study coordinator: Cheng-Feng Lin, Ph.D
- Email: connie@mail.ncku.edu.tw
- Phone: 886-6-2353535
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.