Exercise for managing Fibromyalgia and Irritable Bowel Syndrome

Effects of Indoor Activity on the Integrity and Function of the Intestinal Barrier of Patients With Fibromyalgia and Irritable Bowel Syndrome

Not applicable Interventional Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis · NCT06166563

This study is testing whether a specific exercise program can help adults with Fibromyalgia and Irritable Bowel Syndrome feel better and improve their health.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment165 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorAzienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis Academic / other
Locations1 site (Castellana Grotte, Bari)
Trial IDNCT06166563 on ClinicalTrials.gov

What this trial studies

This project investigates the effects of physical activity as a primary treatment for patients suffering from Fibromyalgia and Irritable Bowel Syndrome. It aims to recruit adult outpatients aged 18-65 from specialized clinics, focusing on those with either condition or both comorbidities. Participants will undergo a comprehensive health assessment and maintain a daily symptom diary to track their progress. The study will evaluate the impact of an exercise program on their symptoms and overall health.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-65 diagnosed with Fibromyalgia, Irritable Bowel Syndrome, or both.

Not a fit: Patients with serious cardiac, hepatic, neurological, psychiatric, or gastrointestinal diseases other than IBS may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve the quality of life for patients suffering from Fibromyalgia and Irritable Bowel Syndrome.

How similar studies have performed: Previous studies have shown promising results for exercise interventions in managing symptoms of Fibromyalgia and Irritable Bowel Syndrome, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Satisfaction of the ACR diagnostic criteria for the diagnosis of FM,
* A total Irritable Bowel Syndrome-Severity Scoring System (IBS-SSS) score of ≥ 125 (moderate to severe IBS symptoms) for the satisfaction of the Rome III-IV criteria in patients with IBS.

Exclusion Criteria:

* Serious cardiac, hepatic, neurological, psychiatric, or gastrointestinal diseases other than IBS (e.g., inflammatory bowel disease, diverticular disease/diverticulitis) that could explain the current symptoms.
* Specific therapy for symptoms due to pathologies (educational programs, alternative medicine, psychotherapy). In the case of subjects who were previously undergoing treatment, they may participate in the study provided they suspend the ongoing therapy until the symptoms reappear.
* The use of drugs to treat FM and IBS.

Where this trial is running

Castellana Grotte, Bari

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions FibromyalgiaIrritable Bowel SyndromeExerciseGastrointestinal FunctionsPhysical Activity
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.