Clinical trial Recruiting at 1 site Observational Ages 18 and up

Exercise Echocardiography Registry for Ischemic and Non-Ischemic Heart Disease

Run by Yonsei University · NCT07367893 · Data updated 2026-11-12

This registry tests how exercise echocardiography findings relate to heart disease in adults with ischemic or non-ischemic conditions during routine care.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment10000 (estimated)
SponsorYonsei University
Academic / other
Locations1 site (Yongin, Gyeonggi-do)
StatusRecruiting
StartedApril 1, 2026
Main results expectedDecember 31, 2030
Study endsDecember 31, 2035
Registry record updatedMay 22, 2026
Trial IDNCT07367893 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 years or older referred for clinically indicated exercise echocardiography to evaluate ischemic or non-ischemic heart disease or related exercise symptoms.

Probably not a fit

Patients unable to perform exercise testing or with non-interpretable imaging, or those not expected to benefit from insights derived from this registry, may not gain direct individual benefits.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, observational registry collecting standardized clinical, exercise, and echocardiographic data from adults undergoing clinically indicated exercise echocardiography at a tertiary care center. It includes patients with suspected or established ischemic heart disease as well as non-ischemic conditions such as cardiomyopathy, heart failure, and valvular disease. The goal is to describe how exercise-induced changes in heart structure and function relate to clinical outcomes in real-world practice. No extra diagnostic procedures are required beyond standard care. Data will be used to better understand prognostic implications of exercise echocardiography across diverse heart diseases.

Why it matters

Potential benefit: If successful, the registry could improve understanding of prognostic indicators from exercise echocardiography and inform clinical decision-making for both ischemic and non-ischemic heart disease.

How similar studies have gone: Prospective exercise echocardiography data have informed practice in ischemic disease; however, real-world, cross-disease registries spanning both ischemic and non-ischemic conditions are less common and ask new questions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 years or older
* Patients referred for clinically indicated exercise echocardiography as part of routine clinical care
* Patients evaluated for suspected or known ischemic heart disease, or non-ischemic heart disease, including but not limited to: Cardiomyopathy, Heart failure, Valvular heart disease, Structural heart disease
* Ability to perform exercise-based stress testing using treadmill or bicycle protocols
* Availability of baseline clinical data and interpretable echocardiographic images obtained during rest and exercise
* Provision of informed consent, or eligibility for consent waiver in accordance with institutional review board approval

Exclusion Criteria:

* Inability to perform exercise testing due to non-cardiac limitations, such as severe orthopedic, neurologic, or pulmonary conditions
* Poor echocardiographic image quality that does not allow meaningful interpretation of exercise-induced changes
* Any condition deemed by the treating physician to make participation inappropriate or unsafe, even within an observational framework

Where it's running

  • Yonsei University Yongin Severance Hospital
    Yongin, Gyeonggi-do, South Korea
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.