Exercise and nutrition program for pancreatic cancer patients
Official title: Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer
Run by H. Lee Moffitt Cancer Center and Research Institute · NCT06423963 · Data updated 2026-11-12
This study is testing a program that combines exercise and nutrition advice for pancreatic cancer patients to see if it helps them get healthier before surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 26 (estimated) |
| Sponsor | H. Lee Moffitt Cancer Center and Research Institute Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Tampa, Florida) |
| Status | Recruiting |
| Started | February 9, 2024 |
| Main results expected | January 2027 |
| Study ends | January 2027 |
| Registry record updated | September 15, 2026 |
| Trial ID | NCT06423963 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older with biopsy-proven borderline resectable pancreatic ductal adenocarcinoma who are undergoing neoadjuvant chemotherapy.
✕Probably not a fit
Patients with significant underlying health issues, such as unstable cardiac or pulmonary disease, or those who regularly engage in resistance training may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study examines the feasibility and acceptability of a prehabilitation program that combines exercise and nutrition counseling for patients preparing for surgery to remove pancreatic cancer. Participants will engage in physical activity, including resistance training, alongside nutritional guidance to enhance their overall health before undergoing surgical resection. The program aims to improve patients' physical condition and potentially their surgical outcomes. The study will assess how well patients can adhere to this program and their satisfaction with it.
Why it matters
Potential benefit: If successful, this program could improve surgical outcomes and recovery for patients with pancreatic cancer.
How similar studies have gone: Other studies have shown positive outcomes with prehabilitation programs in various cancer types, suggesting potential success for this approach in pancreatic cancer.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years or older * Biopsy-proven pancreatic ductal adenocarcinoma (PDAC), borderline resectable at diagnosis * Eastern Cooperative Oncology Group (ECOG) performance status 0-2 * Undergoing neoadjuvant chemotherapy with treatment plan including chemoradiation therapy and surgical resection * Ability to read and speak English Exclusion Criteria: * Regular engagement in RT (2x/week targeting all major muscle groups) * Screen failure for exercise safety based on PAR-Q * Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease * Recent fracture or acute musculoskeletal injury that precludes ability to participate in RT * Numeric pain rating scale greater than or equal to a 7 out of 10 * Myopathic or rheumatologic disease that impacts physical function
Where it's running
-
Moffitt Cancer Center
Tampa, Florida, United States Recruiting
Study contacts
- Principal investigator: Nathan Parker, PhD — Moffitt Cancer Center
- Study coordinator: Morgan Bean
- Email: morgan.bean@moffitt.org
- Phone: 813-745-1786
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.