Exercise and nutrition program for pancreatic cancer patients
Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer
This study is testing a program that combines exercise and nutrition advice for pancreatic cancer patients to see if it helps them get healthier before surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 26 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | H. Lee Moffitt Cancer Center and Research Institute Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Tampa, Florida) |
| Trial ID | NCT06423963 on ClinicalTrials.gov |
What this trial studies
This study examines the feasibility and acceptability of a prehabilitation program that combines exercise and nutrition counseling for patients preparing for surgery to remove pancreatic cancer. Participants will engage in physical activity, including resistance training, alongside nutritional guidance to enhance their overall health before undergoing surgical resection. The program aims to improve patients' physical condition and potentially their surgical outcomes. The study will assess how well patients can adhere to this program and their satisfaction with it.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with biopsy-proven borderline resectable pancreatic ductal adenocarcinoma who are undergoing neoadjuvant chemotherapy.
Not a fit: Patients with significant underlying health issues, such as unstable cardiac or pulmonary disease, or those who regularly engage in resistance training may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could improve surgical outcomes and recovery for patients with pancreatic cancer.
How similar studies have performed: Other studies have shown positive outcomes with prehabilitation programs in various cancer types, suggesting potential success for this approach in pancreatic cancer.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years or older * Biopsy-proven pancreatic ductal adenocarcinoma (PDAC), borderline resectable at diagnosis * Eastern Cooperative Oncology Group (ECOG) performance status 0-2 * Undergoing neoadjuvant chemotherapy with treatment plan including chemoradiation therapy and surgical resection * Ability to read and speak English Exclusion Criteria: * Regular engagement in RT (2x/week targeting all major muscle groups) * Screen failure for exercise safety based on PAR-Q * Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease * Recent fracture or acute musculoskeletal injury that precludes ability to participate in RT * Numeric pain rating scale greater than or equal to a 7 out of 10 * Myopathic or rheumatologic disease that impacts physical function
Where this trial is running
Tampa, Florida
- Moffitt Cancer Center — Tampa, Florida, United States (Recruiting)
Study contacts
- Principal investigator: Nathan Parker, PhD — Moffitt Cancer Center
- Study coordinator: Morgan Bean
- Email: morgan.bean@moffitt.org
- Phone: 813-745-1786
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.