Exercise and blood pressure in people with thoracic aortic aneurysm

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with thoracic aortic aneurysm will participate in a supervised exercise program targeted at about 80% of the anaerobic threshold, with periodic monitoring of blood pressure and safety. Anthropometric and body composition measures plus blood pressure responses will be recorded at baseline, 3 months, and 6 months to quantify changes over time. The protocol excludes patients with large or rapidly growing aneurysms, connective tissue disorders, significant renal impairment, or other major cardiovascular or musculoskeletal limitations. The main goals are to describe the blood pressure behavior during and after the exercise program and to document the intervention's safety in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years and older
* Have an interest in participating in a supervised exercise training program
* Aortic diameter between 3,5 and 5 cm

Exclusion Criteria

* Glomerular filtration rate below 30 mL/min/1.73m²
* Aortic diameter greater than or equal to 5.1 cm
* Progression of aortic diameter greater than or equal to 0.5 cm per year
* Allergy to iodine
* Aortic valve bicuspidy
* History of aortic surgery or cardiac surgery
* Presence of an aortic dissection, penetrating aortic ulcer, or intra-mural hematoma of the aorta
* Presence of Marfan syndrome or other genetic and/or congenital disease explaining the thoracic aortic aneurysm
* History of stroke
* Presence of peripheral artery disease
* History and/or presence of aortitis
* Known diagnosis of temporal arteritis or rheumatoid arthritis
* Presence of a pacemaker
* Major cognitive limitation that may affect adherence to visits
* Musculoskeletal limitation that restricts participation in the training program

Where it's running

• Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval
  Québec, Quebec, Canada Recruiting
• Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval
  Québec, Quebec, Canada Not yet recruiting

Study contacts

• Principal investigator: Paul Poirier, MD — Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
• Study coordinator: Paul Poirier, MD
• Email: paul.poirier@criucpq.ulaval.ca
• Phone: (418) 656-4767

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.