Examining voice changes in trans men during hormone therapy
Investigation of the Perceptual and Acoustic Characteristic of Voice in Trans Man
Hacettepe University · NCT05166083
This study is testing how hormone therapy affects the voices of trans men to see what changes happen during treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 28 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | Female |
| Sponsor | Hacettepe University (other) |
| Locations | 1 site (Ankara) |
| Trial ID | NCT05166083 on ClinicalTrials.gov |
What this trial studies
This observational study aims to track the acoustic and perceptual changes in the voices of trans men undergoing hormone therapy. Participants will be evaluated at baseline and after the 4th and 8th doses of testosterone, with assessments including videolaryngostroboscopy and self-report scales during psychiatric visits. The study will analyze the relationship between testosterone levels and both psychosocial and vocal characteristics over the course of treatment. A total of 28 participants will be included, and various statistical methods will be employed to analyze the collected data.
Who should consider this trial
Good fit: Ideal candidates for this study are trans men diagnosed with gender dysphoria who have decided to start hormone therapy.
Not a fit: Patients with vocal fold lesions, prior voice therapy or surgery, or those with neurological disorders affecting voice quality may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into how hormone therapy affects voice characteristics in trans men, potentially improving treatment approaches.
How similar studies have performed: While there is limited research specifically focused on voice changes in trans men during hormone therapy, similar studies in transgender populations have shown promising results in understanding vocal changes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being diagnosed with "Gender Dysphoria" according to DSM 5 * Having decided to start hormone therapy Exclusion Criteria: * Diagnosis of vocal fold lesion in videolaryngostroboscopy evaluation * Having previously received voice therapy or undergone voice surgery * Having a systematic/or neurological disorder that may affect voice quality * Having had hormone therapy or still on hormone therapy
Where this trial is running
Ankara
- Hacettepe University, Speech and Language Therapy — Ankara, Turkey (RECRUITING)
Study contacts
- Study coordinator: Fatma Esen AYDINLI, Assoc. Prof.
- Email: fesen04@hacettepe.edu.tr
- Phone: +903123051093
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gender Dysphoria, Voice Disorder Due to Transsexualism, Transgender Persons, Hormone Replacement Therapy, Trans man voice, hormon therapy