Clinical trial Recruiting at 1 site Observational Ages 6 Months to 90

Examining visual function in children with amblyopia and strabismus during treatment

Official title: Oculomotor Disorders: Experimental and Clinical Study

Run by The Cleveland Clinic · NCT04310241 · Data updated 2026-11-12

This study is testing how different treatments for amblyopia and strabismus, like patching and glasses, can improve vision in children by checking their eye movements and clarity before and after treatment.

Quick facts

Study typeObservational
Ages6 Months to 90 Years
SexAll
Enrollment150 (estimated)
SponsorThe Cleveland Clinic
Academic / other
Locations1 site (Cleveland, Ohio)
StatusRecruiting
StartedFebruary 21, 2020
Main results expectedMarch 12, 2027
Study endsMarch 12, 2027
Registry record updatedMarch 4, 2026
Trial IDNCT04310241 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are children with a history of amblyopia or those exhibiting amblyogenic risk factors.

Probably not a fit

Patients with a history of neurologic disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to quantify various visual functions in children diagnosed with amblyopia and strabismus. Participants will undergo a series of visual function tests, including eye movements, contrast sensitivity, and visual acuity, both before and after treatment interventions such as patching therapy and glasses. The study will also assess the impact of strabismus surgery on visual functions. Measurements will be repeated throughout the treatment process to evaluate changes in visual capabilities.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and treatment strategies for children with amblyopia and strabismus, enhancing their visual outcomes.

How similar studies have gone: Other studies have shown success in measuring visual function improvements in similar patient populations, indicating that this approach is supported by prior research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* History of amblyopia or presence of amblyogenic risk factors.

Exclusion Criteria:

* History of neurologic disorders

Where it's running

  • Cleveland Clinic
    Cleveland, Ohio, United States
    Recruiting

Study contacts

  • Principal investigator: Fatema Ghasia, MD — The Cleveland Clinic
  • Study coordinator: Kimberly Baynes, MSN
  • Email: baynesk@ccf.org
  • Phone: 216-444-2566

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.