Examining visual function in children with amblyopia and strabismus during treatment
Official title: Oculomotor Disorders: Experimental and Clinical Study
Run by The Cleveland Clinic · NCT04310241 · Data updated 2026-11-12
This study is testing how different treatments for amblyopia and strabismus, like patching and glasses, can improve vision in children by checking their eye movements and clarity before and after treatment.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 6 Months to 90 Years |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | The Cleveland Clinic Academic / other |
| Locations | 1 site (Cleveland, Ohio) |
| Status | Recruiting |
| Started | February 21, 2020 |
| Main results expected | March 12, 2027 |
| Study ends | March 12, 2027 |
| Registry record updated | March 4, 2026 |
| Trial ID | NCT04310241 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are children with a history of amblyopia or those exhibiting amblyogenic risk factors.
✕Probably not a fit
Patients with a history of neurologic disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to quantify various visual functions in children diagnosed with amblyopia and strabismus. Participants will undergo a series of visual function tests, including eye movements, contrast sensitivity, and visual acuity, both before and after treatment interventions such as patching therapy and glasses. The study will also assess the impact of strabismus surgery on visual functions. Measurements will be repeated throughout the treatment process to evaluate changes in visual capabilities.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and treatment strategies for children with amblyopia and strabismus, enhancing their visual outcomes.
How similar studies have gone: Other studies have shown success in measuring visual function improvements in similar patient populations, indicating that this approach is supported by prior research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * History of amblyopia or presence of amblyogenic risk factors. Exclusion Criteria: * History of neurologic disorders
Where it's running
-
Cleveland Clinic
Cleveland, Ohio, United States Recruiting
Study contacts
- Principal investigator: Fatema Ghasia, MD — The Cleveland Clinic
- Study coordinator: Kimberly Baynes, MSN
- Email: baynesk@ccf.org
- Phone: 216-444-2566
Similar studies
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This study tests a computer-based Gabor training program to see if it can improve vision in adults aged 18–39 with amblyopia due to anisometropia or strabismus.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.