Examining the role of specific gene signaling in colorectal cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on understanding the roles of exosomal Circ-LRBA and the 451/CRTC2 signaling axis in colorectal cancer. It aims to investigate the molecular mechanisms underlying colorectal cancer progression and identify potential biomarkers that could aid in predicting patient prognosis. By analyzing gene expression changes in patients who have undergone radical surgical resection for colorectal cancer, the study seeks to enhance the selection of targeted therapies for better treatment outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1.18-80 years old.

2.18.5 \< BMI \< 27.9.

3\. The surgical methods are radical resection of rectal cancer, resection of right colon cancer, resection of left colon cancer and radical resection of sigmoid colon cancer.

Exclusion Criteria:

1. Those who refuse to collect samples.
2. Patients with severe dysfunction of coagulation, hepatorenal dysfunction or severe cardiopulmonary diseases.
3. Patients who has a history of neoadjuvant radiotherapy or chemotherapy.
4. Combining with distant multiple metastases of tumor

Where it's running

• The First Affiliated Hospital of Shandong First Medical University
  Jinan, Lixia, China Recruiting

Study contacts

• Study coordinator: Jingbo Chen, doctor
• Email: qychenjingbo@163.com
• Phone: 15053186972

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.