Examining the Mitral Splay Sign and Its Link to Mitral Regurgitation Severity

Study of Splay Sign in Mitral Regurgitation and Other Valve Lesions as Related to Its Mechanisms, Predictors of Its Occurence and Association With Severity of Mitral Regurgitation

Observational ITMO University · NCT06152315

This study is testing if a specific sign seen on heart ultrasound can help doctors understand how severe mitral regurgitation is in patients.

Quick facts

Study typeObservational
Enrollment80 (estimated)
Ages18 Years and up
SexAll
SponsorITMO University Academic / other
Locations1 site (Tarusa, Kaluga Region)
Trial IDNCT06152315 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the echocardiographic splay sign in patients with mitral regurgitation and its correlation with the severity of the condition. By analyzing echocardiographic data, the study seeks to understand the mechanism behind the splay sign and its association with a specific Doppler artifact known as the 'seagull cry.' The study will include patients undergoing echocardiography for clinical reasons, focusing on the quality and interpretability of the echocardiographic recordings.

Who should consider this trial

Good fit: Ideal candidates for this study are patients undergoing echocardiography for clinical indications related to mitral regurgitation.

Not a fit: Patients with poor quality echocardiographic recordings or those for whom the severity of mitral regurgitation cannot be determined may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of mitral regurgitation severity assessment, leading to improved patient management.

How similar studies have performed: There is limited information on similar studies, making this approach relatively novel in the context of mitral regurgitation assessment.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* any patient undergoing echocardiography for clinical indications

Exclusion Criteria:

* poor quality of recorded echocardiography study
* inability to ascertain severity of mitral regurgitation

Where this trial is running

Tarusa, Kaluga Region

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mitral Regurgitationechocardiographysplay signseagull cry
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.