Examining the microbiological diversity in exhaled air of COPD and non-COPD patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze the microbiological diversity present in the exhaled air of patients with chronic obstructive pulmonary disease (COPD) and those without the condition. Participants will be recruited during medical visits in the Departments of Pneumology and Occupational and Environmental Pathologies, where their clinical data, health status, and smoking history will be collected. Exhalation samples will be taken from different groups based on their health status, age, and smoking habits, with a follow-up collection scheduled for one year later.

Why it matters

Who can join: the full rules

Inclusion Criteria:

For COPD:

* Patients with chronic obstructive pulmonary disease
* Age: over 18

For non-COPD

* Absence of chronic obstructive pulmonary disease
* Age: between 18 and 30 years old and between 45 and 70 years old

Exclusion Criteria:

* Taking certain medications in the month preceding the sample (antibiotics, systemic corticosteroids, immunosuppressants)
* Person under guardianship or curatorship
* Pregnant or breastfeeding women
* Person unable to express his/her opposition, person deprived of liberty
* Existence of a chronic infectious pulmonary pathology such as (dilation of the bronchi, cystic fibrosis)

Where it's running

• Centre Hospitalier Intercommunal de Créteil
  Créteil, France Recruiting

Study contacts

• Principal investigator: Jean Claude PAIRON, PhD — CHI créteil
• Study coordinator: Jean-Claude PAIRON, PhD
• Email: jc.pairon@chicreteil.fr
• Phone: 01 45 02 20 93

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Flutter therapy added to chest physiotherapy after CABG in COPD patients

  This study tests whether adding Flutter therapy to standard chest physiotherapy helps post-CABG patients with mild-to-moderate COPD improve breathing more than chest physiotherapy alone.

  Recruiting Foundation University Islamabad · Rawalpindi · NCT07875049

• TPB-based cadence exercise and breathing training for COPD patients

  A TPB-based program tests whether breathing training, cadence-guided walking, or both can improve lung function, exercise capacity, and quality of life in adults with COPD.

  Recruiting Fu Jen Catholic University Hospital · New Taipei City, New Taipei City and 1 other locations · NCT07860008

• See how dynamic chest X-rays relate to COPD patterns and progression risk

  This study looks at existing dynamic chest radiography data to see if new imaging measurements can identify COPD patterns, gauge severity, and predict who may experience faster progression.

  Recruiting Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong · NCT07762573

• Personalized mobile app warnings to reduce COPD flares

  A personalized mobile app tests whether providing temperature-related risk warnings and protective tips, in addition to usual COPD care, can lower COPD flare-ups over 12 months.

  Recruiting at 4 sites Centers for Disease Control and Prevention, China · Beijing and 3 other locations · NCT07656142

• CLEAR model to predict when people with severe COPD can be taken off ventilatory support

  This project will see if the CLEAR model can predict which adults with severe COPD on invasive or non‑invasive ventilation can be safely taken off ventilatory support.

  Recruiting Assiut University · Asyut, Assuit Egypt · NCT07579052

• Long-term safety of Tozorakimab in COPD patients with prior exacerbations

  This study tests two long-term dosing regimens of tozorakimab in people with COPD who have a history of flare-ups and who completed earlier studies.

  Recruiting at 5 sites Phase 3 AstraZeneca · Aix-en-Provence and 12 other locations · NCT07566195

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.