Examining the link between progesterone levels and live birth rates
The Correlation Between Luteal Serum Progesterone and Live Birth Rate in IVF - a Prospective Cohort Study (LUT-2)
This study is trying to see if measuring progesterone levels in patients undergoing embryo transfer can help predict their chances of having a live birth.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years to 41 Years |
| Sex | Female |
| Sponsor | Regionshospitalet Viborg, Skive Academic / other |
| Locations | 1 site (Skive) |
| Trial ID | NCT05323513 on ClinicalTrials.gov |
What this trial studies
This observational cohort study aims to investigate the relationship between serum progesterone levels and the likelihood of achieving a live birth in patients undergoing embryo transfer. Serum progesterone will be measured on day OR+4 and again on the day of embryo transfer, which occurs on either day OR+3 or OR+5. By analyzing these hormone levels, the study seeks to provide insights into how progesterone may influence fertility outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are women undergoing embryo transfer with a BMI of less than 35 kg/m2.
Not a fit: Patients who have undergone a fresh embryo transfer or those who have previously participated in this study may not benefit.
Why it matters
Potential benefit: If successful, this study could help optimize fertility treatments by identifying progesterone levels that are associated with higher live birth rates.
How similar studies have performed: While there have been studies examining hormone levels in relation to fertility, this specific correlation between luteal serum progesterone and live birth rates is less commonly explored, making this approach somewhat novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Signed informed consent * BMI \<35kg/m2 Exclusion Criteria: * No fresh embryo transfer * Prior participation in the study
Where this trial is running
Skive
- Fertilitetsklinikken, Regionshospitalet Skive — Skive, Denmark (Recruiting)
Study contacts
- Principal investigator: Peter Humaidan, Professor — Fertilitetsklinikken, Regionshospitalet Skive
- Study coordinator: Peter Humaidan, Professor
- Email: peter.humaidan@midt.rm.dk
- Phone: 78445760
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.