Examining the link between pain and blood markers after inguinal hernia surgery
Relationship Between Acute Phase Markers and Post-operative Pain in Open Tension-free Inguinal Hernia Repair: An Observational Study
This study is trying to see if certain blood markers can help predict how much pain people feel after having inguinal hernia surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 71 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Roma La Sapienza Academic / other |
| Locations | 1 site (Roma) |
| Trial ID | NCT06380140 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between acute phase markers in the blood and post-operative pain experienced by patients undergoing open tension-free inguinal hernia repair. By analyzing serum markers such as leukocytes, C-reactive protein, D-dimer, fibrinogen, and the neutrophil-to-lymphocyte ratio, the study aims to predict pain severity and tailor pain relief therapies accordingly. Pain levels will be assessed at multiple time points following surgery to establish any correlations with the measured markers.
Who should consider this trial
Good fit: Ideal candidates for this study are adults undergoing open tension-free inguinal hernia repair.
Not a fit: Children and individuals not undergoing the specified surgical procedure may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective pain management strategies for patients after inguinal hernia repair.
How similar studies have performed: While the approach of correlating blood markers with pain levels is not widely tested, similar studies have shown promise in other surgical contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patient undergoing Open Tension-free Inguinal Hernia Repair Exclusion Criteria: * children
Where this trial is running
Roma
- Augusto Lauro — Roma, Italy (Recruiting)
Study contacts
- Study coordinator: Augusto Lauro
- Email: augusto.lauro@uniroma1.it
- Phone: +39 338 8663 879
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.