Examining the link between high uric acid levels and psoriatic arthritis
IImpact of Hyperuricemia on Psoriatic Arthritis
This study is trying to see if high uric acid levels make psoriatic arthritis worse for people who have the condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 242 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Trial ID | NCT06125444 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between hyperuricemia and the severity of psoriatic arthritis. It aims to determine if high uric acid levels are associated with worse outcomes in patients with psoriatic arthritis, based on medical records and serum uric acid assays. The findings could lead to new recommendations for managing hyperuricemia in these patients, potentially altering treatment approaches. The study will include patients who have been diagnosed with psoriatic arthritis and have relevant medical data available.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a confirmed diagnosis of psoriatic arthritis and available serum uric acid data.
Not a fit: Patients who do not have psoriatic arthritis or those who oppose the reuse of their medical data for research will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for patients with psoriatic arthritis who also have high uric acid levels.
How similar studies have performed: While the link between hyperuricemia and psoriatic arthritis is hypothesized, this specific investigation is novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * Major subject (≥18 years old) * Subject with a history of psoriatic arthritis objectified according to the CIM 10-1 coding for patients followed in hospitalization at the HUS and HCC * Subject presenting psoriatic arthritis objectified during a consultation by an HCC rheumatologist * Among these two populations, all subjects for whom at least one serum uric acid assay was available in the medical file * Subject having not expressed, after being informed, opposition to the reuse of their data for research purposes Exclusion criteria: * Subject who expressed their opposition to participating in the study * Subject who met the inclusion criteria but whose analysis of the medical file (anamnestic, clinical, biological and radiological data) led to a diagnostic reversal and therefore did not present with psoriatic arthritis * Subject under guardianship or curatorship * Subject under safeguard of justice
Where this trial is running
Strasbourg
- Service de Rhumatologie - CHU de Strasbourg - France — Strasbourg, France (Recruiting)
Study contacts
- Study coordinator: Renaud FELTEN, MD
- Email: renaud.felten@chru-strasbourg.fr
- Phone: 33 3 88 12 79 64
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.