Examining the link between H. pylori infection and kidney disease
Correlation Between Endoscopic Findings And Helicobacter Pylori Infection In Chronic Kidney Disease Patients
This study is trying to see if people with chronic kidney disease are more likely to have an H. pylori infection and what stomach problems might come with it.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT05927766 on ClinicalTrials.gov |
What this trial studies
This study evaluates the frequency of Helicobacter pylori infection in patients with chronic kidney disease (CKD) and describes the gastroduodenal lesions associated with this infection. It employs a cross-sectional approach to investigate the relationship between H. pylori and CKD, addressing conflicting hypotheses regarding their association. The study aims to clarify whether CKD influences the prevalence of H. pylori infection and the resulting gastric conditions. Patients with CKD stages 3 to 5 will be compared to a control group without CKD to assess these correlations.
Who should consider this trial
Good fit: Ideal candidates include patients with chronic kidney disease classified as stages 3 to 5, whether on hemodialysis or not.
Not a fit: Patients with multiple comorbidities, malignant diseases, or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve understanding of H. pylori infection in CKD patients, potentially leading to better management strategies.
How similar studies have performed: While there have been debates regarding the association of H. pylori and CKD, this study explores a relatively novel area with limited prior research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with CKD classified as stages 3 to 5 according Kidney Disease Improving Global Outcomes classification, on hemodialysis or not. * control group without chronic kidney disease. Exclusion Criteria: * frail patients with multiple comorbidities or malignant disease. * pregnant ladies. * patients recently on proton pump inhibitors two weeks or less prior to the interview.
Where this trial is running
Sohag
- Sohag university hospital — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: mohamed f ebdalla, dr
- Email: mohamedfaisel@med.sohag.edu.eg
- Phone: 01062271010
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.