Examining the link between blood markers and eye blood flow in diabetic patients
Correlation of Biochemical Indexes and Retinal Hemodynamic in Patients With Different Degrees of Diabetic Retinopathy
The Seventh Affiliated Hospital of Sun Yat-sen University · NCT05902650
This study looks at how certain blood markers relate to blood flow in the eyes of people with diabetes to help predict the risk of diabetic retinopathy.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | The Seventh Affiliated Hospital of Sun Yat-sen University (other) |
| Locations | 1 site (Shenzhen, Guangdong) |
| Trial ID | NCT05902650 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on diabetic patients at the Department of Ophthalmology of the Seventh Affiliated Hospital of Sun Yat-sen University. It collects OCTA data and biochemical indexes to develop a prediction model for diabetic retinopathy using the random forest method to identify sensitive indicators. The goal is to better understand how these factors correlate with different degrees of diabetic retinopathy.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with a clinical diagnosis of diabetes.
Not a fit: Patients with other retinal diseases or those who have undergone intraocular surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection and management of diabetic retinopathy in patients.
How similar studies have performed: While similar studies have explored the relationship between biochemical markers and diabetic retinopathy, this specific approach using random forest modeling is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of diabetes Exclusion Criteria: * various other types of retinal and choroidal disease; * history of any intraocular surgery or treatment (including intravitreal injection, retinal photocoagulation etc. * with severe refractive medium opacity that could affect fundus examination.
Where this trial is running
Shenzhen, Guangdong
- The Seventh Affiliated Hospital, Sun Yat-sen University — Shenzhen, Guangdong, China (RECRUITING)
Study contacts
- Principal investigator: Mingzhe Cao — The Seventh Affiliated Hospital of Sun Yat-sen University
- Study coordinator: Mingzhe Cao, Dr.
- Email: zhengz@mail.sysu.edu.cn
- Phone: 13060822790
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Diabetic Retinopathy