Examining the impact of iodine nutrition on thyroid cancer outcomes
Prospective Cohort Study on Clinical Characteristics of Thyroid Cancer in Different Iodine Status Areas
This study looks at how iodine levels in different areas affect the outcomes and characteristics of thyroid cancer in patients who have had thyroid surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1600 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Shandong Provincial Hospital Government |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT06623500 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between iodine nutritional status and clinical characteristics of thyroid cancer. It involves a prospective cohort of patients who underwent thyroid surgery in various regions with differing iodine levels from 2012 to 2019. The study aims to analyze how regional iodine nutrition influences the pathological types, clinical features, and prognosis of thyroid cancer. Patients are recruited from selected sub-centers in high and moderate iodine areas, ensuring a comprehensive understanding of iodine's role in thyroid cancer.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 65 who have lived in the selected iodine regions for at least 5 years and have been diagnosed with thyroid cancer.
Not a fit: Patients with other types of cancer, serious comorbidities, or those unable to provide follow-up information may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into how iodine nutrition affects thyroid cancer prognosis, potentially guiding dietary recommendations for patients.
How similar studies have performed: While the relationship between iodine nutrition and thyroid cancer has been debated, this study's specific approach is novel and may provide new insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age range: 18\~65 years old, gender not limited; 2. Living in the selected region for at least 5 years; 3. Patients who underwent thyroid surgery at various research centers were pathologically diagnosed with thyroid cancer; 4. The clinical data （general information、surgical scope 、pathological report、utrasonic report, etc ）of the case is complete. Exclusion Criteria: 1. Diagnosed as other types of cancer or thyroid metastatic cancer; 2. There are serious comorbidities such as heart, liver, and kidney diseases present; 3. Unable to follow up on prognostic information.
Where this trial is running
Jinan, Shandong
- Shandong Provincial Hospital — Jinan, Shandong, China (Recruiting)
Study contacts
- Study coordinator: Qingling Guo
- Email: guoqinglingqhb@163.com
- Phone: +86 0531-68776375
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.