Examining the effects of stress on adults with Tourette Syndrome
Longitudinal Impact of Stressors in Adults With Tourette Syndrome
This study looks at how stress affects adults with Tourette Syndrome over two years to see if it changes their tics, mental health, and overall quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 140 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Vanderbilt University Medical Center Academic / other |
| Locations | 1 site (Nashville, Tennessee) |
| Trial ID | NCT04851678 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the long-term impact of environmental stressors on adults with Tourette Syndrome (TS) over a two-year period. It will assess how lifetime exposure to stress affects tic severity, psychiatric comorbidities, and overall health-related quality of life. The study will include adults over 18 who meet the diagnostic criteria for TS or related disorders, and it will gather data through interviews and assessments without any interventions. The findings could provide valuable insights into the challenges faced by adults with TS and inform future treatment approaches.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 who have been diagnosed with Tourette Syndrome or related tic disorders.
Not a fit: Patients with significant medical, neurologic, or psychiatric conditions other than Tourette Syndrome may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of how stress influences the lives of adults with Tourette Syndrome, potentially leading to improved support and interventions.
How similar studies have performed: While there is limited research specifically on the impact of stress in adults with Tourette Syndrome, studies on stress and its effects on mental health have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * adults (\>18) meeting Diagnostic and Statistics Manual, 5th edition (DSM-V) criteria for Tourette syndrome, chronic motor tic disorder, or chronic vocal tic disorder * ability to provide informed consent * English proficiency Exclusion Criteria: \- significant medical, neurologic, or psychiatric diagnoses (e.g. uncontrolled epilepsy, chronic heart failure, schizophrenia) besides TS and its commonly co-occurring psychiatric diagnoses
Where this trial is running
Nashville, Tennessee
- Vanderbilt University Medical Center — Nashville, Tennessee, United States (Recruiting)
Study contacts
- Principal investigator: David A Isaacs, MD, MPH — Vanderbilt University Medical Center
- Study coordinator: Michelle Eckland, BS
- Email: michelle.r.eckland.1@vumc.org
- Phone: 615-875-7394
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.