Examining the effects of sinus surgery on cystic fibrosis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the outcomes of endoscopic sinus surgery in patients with cystic fibrosis who suffer from chronic rhinosinusitis. It includes a control group of patients receiving medical treatment for their condition. The study will assess various outcomes, including pulmonary function and quality of life, to determine the impact of surgical intervention compared to medical management. Participants will be monitored over time to evaluate their health status and treatment preferences.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Subjects between the ages of 18 years old (inclusive) and 99 years old (inclusive, subjects over the age of 89 will be recorded to be 89 years old).
2. Diagnosed with cystic fibrosis as established by genetic testing combined with clinical assessment and/or sweat chloride
3. Diagnosed with chronic rhinosinusitis by multidisciplinary sinusitis guidelines
4. chronic rhinosinusitis symptoms persisting beyond initial medical treatment
5. Counseled for endoscopic sinus surgery and ongoing medical therapy with each patient electing their preferred treatment

Exclusion Criteria:

1. Underwent endoscopic sinus surgery in past 12 months
2. Will obtain follow up care at non-participating institutions
3. Unable to complete follow-up surveys

Where it's running

• University of California, Los Angeles
  Los Angeles, California, United States Recruiting
• Stanford University
  Stanford, California, United States Recruiting
• University of Colorado
  Aurora, Colorado, United States Recruiting
• National Jewish Health
  Denver, Colorado, United States Recruiting
• University of North Carolina
  Chapel Hill, North Carolina, United States Recruiting
• Oregon Health Science University
  Portland, Oregon, United States Recruiting

Study contacts

• Principal investigator: Daniel M Beswick, MD — University of California, Los Angeles
• Study coordinator: Daniel M Beswick, MD
• Email: dbeswick@mednet.ucla.edu
• Phone: 310-206-8457

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• PALMIRE cohort: phenotyping inflammatory lung diseases to enable personalized care

  This project will collect clinical, imaging, and biological data from adults with asthma, COPD, bronchiectasis, cystic fibrosis, primary ciliary dyskinesia, or interstitial lung disease to try to identify disease subtypes and markers that could guide more personalized care.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.