Examining the effects of different proteins on blood sugar levels
Comprehensive Study of Biochemical Response to Alternative Protein Sources in Different Food Matrices
This study is testing how different types of protein-rich foods affect blood sugar levels and gut health in people at risk for type 2 diabetes.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 30 Years to 65 Years |
| Sex | All |
| Sponsor | University of Eastern Finland Academic / other |
| Locations | 1 site (Kuopio) |
| Trial ID | NCT06253728 on ClinicalTrials.gov |
What this trial studies
This research investigates how various protein and fiber-rich foods affect glucose metabolism and gut health in individuals at risk for type 2 diabetes. Participants will undergo a controlled postprandial intervention where their plasma amino acids, lipids, and glucose levels will be monitored after consuming high fiber and protein meals. The study aims to compare the effects of plant-based versus animal-based proteins on metabolic responses and gut microbiota. Additionally, in vitro experiments will analyze the differences in metabolites produced by these proteins in the gut.
Who should consider this trial
Good fit: Ideal candidates are adults aged 30-65 with a BMI between 25 and 35 who are at risk for type 2 diabetes.
Not a fit: Patients with chronic diseases requiring regular medication, such as type 2 diabetes, or those following a gluten-free or vegan diet may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to dietary recommendations that improve blood sugar control and overall health for individuals at risk of type 2 diabetes.
How similar studies have performed: Other studies have shown promising results in understanding the impact of dietary proteins on metabolic health, suggesting this approach has potential.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 30-65 years of age * BMI \>25 kg/m2 and \<35 kg/m2 * Waist circumference with females \>85 cm and with males \>100 cm Exclusion Criteria: * Certain chronic diseases requiring regular medication (e.g., type 2 diabetes, chronic liver, kidney, thyroid, or gastrointestinal diseases) * Pregnancy or breastfeeding * Gluten-free or vegan diet * Use of antibiotics within the last 12 months * Gastrointestinal surgery within the last two years * High alcohol consumption
Where this trial is running
Kuopio
- University of Eastern Finland — Kuopio, Finland (Recruiting)
Study contacts
- Principal investigator: Marjukka Kolehmainen, Professor — University of Eastern Finland
- Study coordinator: Marjukka Kolehmainen, Professor
- Email: marjukka.kolehmainen@uef.fi
- Phone: 0403553617
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.