Examining pregnancy outcomes in women with congenital heart disease
Pregnancy Outcomes in Patients With Adult Congenital Heart Disease
This study is trying to see if blood tests taken during pregnancy can help predict heart risks for women who have congenital heart disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT06678256 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess whether biomarker assays collected during pregnancy can predict cardiovascular risks in women with congenital heart disease. It will analyze samples taken during the first to third trimesters and postpartum to evaluate changes in biomarker levels over time. The goal is to improve risk prediction for cardiovascular adverse events by comparing these temporal changes to single time-point assessments.
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant women diagnosed with congenital heart disease.
Not a fit: Patients who are not currently pregnant or unable to provide consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better risk assessment and management strategies for pregnant women with congenital heart disease.
How similar studies have performed: While this approach is novel in the context of pregnancy and congenital heart disease, similar biomarker studies have shown promise in other cardiovascular contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Congenital Heart Disease Diagnosis * Currently Pregnant Exclusion Criteria: * Unable to consent
Where this trial is running
Rochester, Minnesota
- Mayo Clinic in Rochester — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Alexander Egbe, MBBS, MPH — Mayo Clinic
- Study coordinator: Jolene Tuchek
- Email: Tuchek.Jolene@mayo.edu
- Phone: 507-538-5488
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.