Examining plaque characteristics in patients deferred from coronary intervention

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between coronary computed tomography angiography (CTA) defined high-risk plaque characteristics and future cardiac events in patients who have been deferred from percutaneous coronary intervention (PCI) based on fractional flow reserve (FFR) measurements. The study aims to identify plaque features that may predict long-term cardiac outcomes in these patients. By analyzing data from patients with chronic coronary syndromes (CCS) who underwent CTA prior to invasive coronary angiography, the researchers hope to uncover factors that contribute to cardiac events despite initial deferral. This could lead to improved risk stratification and management strategies for patients with similar profiles.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* men and women aged ≥20 years,
* patients having chronic coronary syndromes (CCS,
* Coronary computed tomography angiography (CTA) was performed within 90 days before invasive coronary angiography (ICA) with fractional flow reserve (FFR) pressure measurement.

Exclusion Criteria:

* patients with a history of coronary bypass grafting (CABG) because CABG changed local coronary flow dynamics,
* patients with left-main disease,
* patients with fractional flow reserve (FFR) in stented vessels due to inability to estimate plaque morphology in the stented lesion by coronary computed tomography angiography.

Where it's running

• Fujita Health University
  Toyoake, Aichi-ken, Japan Recruiting

Study contacts

• Principal investigator: YUKIO OZAKI, MD, PhD — Fujita Health University, Aichi, Japan
• Study coordinator: YUKIO OZAKI, MD, PhD
• Email: yukio.ozaki7@gmail.com
• Phone: 08030713131

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.