Clinical trial Recruiting at 1 site Observational Ages 18 and up

Examining personality traits in adults with autism

Official title: DSM-5 Personality Disorders in Adults With Autism

Run by Parnassia Groep · NCT06726187 · Data updated 2026-11-12

This study is testing how well adults with autism understand their own personality traits compared to what others say about them.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment102 (estimated)
SponsorParnassia Groep
Academic / other
Locations1 site (Rotterdam)
StatusRecruiting
StartedMarch 1, 2024
Main results expectedJanuary 28, 2027
Study endsJanuary 29, 2027
Registry record updatedJuly 17, 2026
Trial IDNCT06726187 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older with a primary diagnosis of Autism Spectrum Disorder and no intellectual disability.

Probably not a fit

Patients with current substance abuse, psychotic disorders, or those who do not meet the criteria for ASD may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the agreement between self-reported and informant-reported DSM-5 personality disorder traits in adults diagnosed with Autism Spectrum Disorder (ASD). Participants will complete the Structured Clinical Interview for DSM-5 Screening Personality Questionnaire (SCID-5-SPQ) to assess their personality traits. The study aims to enhance the reliability of self-report measures, which are crucial for both research and clinical assessments in this population. By comparing self-reports with those of informants, the study seeks to provide insights into the accuracy of self-perception among adults with ASD.

Why it matters

Potential benefit: If successful, this study could improve the accuracy of personality assessments in adults with autism, leading to better tailored clinical services.

How similar studies have gone: While there is limited research specifically on this topic, studies examining self-report versus informant-report in other populations have shown varying degrees of success, indicating the potential for valuable insights in this area.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria Inclusion criteria for ASD participants: (1) primary diagnosis of ASD according to the DSM-5-TR, (2) age 18+ years, (3) no intellectual disability, and (4) at least having completed a primary and secondary education.

Inclusion criteria for informants:

Participants were asked to identify individuals who knew them well and were capable of providing accurate descriptions of their personality traits, preferably informants that cohabited with the participants. When cohabitants were unavailable, participants were asked to identify "the person who knows you best." Additionally, eligibility of informants for inclusion required that, historically, the informant and the participant talked at least monthly and interacted face-to-face at least yearly.

Exclusion criteria Exclusion criteria for ASD participants: (1) no ASD diagnosis, (2) current substance abuse, (3) psychotic disorders, (4) schizophrenia, (5) eating disorder, (6), mental retardation (IQ\<80), (7) suicidal ideations and (8) age \<18 years.

Exclusion criteria for informants: (1) age \<18 years, (2) intellectual disability, and (3) not being able to state and/or recognize psychological and problematic functioning of their participating relative with ASD.

Where it's running

  • Sarr - Parnassia Groep Antes
    Rotterdam, Netherlands
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.