Examining pain levels after laparoscopic gallbladder surgery and their relation to blood markers

Relationship Between Acute Phase Markers and Acute Post-operative Pain in Laparoscopic Cholecystectomy: An Observational Study

Observational University of Roma La Sapienza · NCT06375057

This study looks at how certain blood markers relate to pain levels after gallbladder surgery to help find better ways to manage pain for patients.

Quick facts

Study typeObservational
Enrollment54 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Roma La Sapienza Academic / other
Locations1 site (Roma)
Trial IDNCT06375057 on ClinicalTrials.gov

What this trial studies

This observational study investigates the relationship between acute phase proteins and post-operative pain in patients who have undergone laparoscopic cholecystectomy. By analyzing serum markers such as leukocytes, C-reactive protein, D-dimer, fibrinogen, and the neutrophil-to-lymphocyte ratio, the study aims to predict pain severity and identify the most suitable pain relief therapies. Pain levels will be assessed at multiple time points post-surgery, allowing for a comprehensive understanding of pain dynamics over time.

Who should consider this trial

Good fit: Ideal candidates for this study are adults scheduled for laparoscopic cholecystectomy.

Not a fit: Children and individuals not undergoing laparoscopic cholecystectomy will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing laparoscopic cholecystectomy.

How similar studies have performed: While the approach of correlating blood markers with pain levels is not widely tested, similar studies have shown promise in understanding post-operative pain.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patient undergoing laparoscopic cholecystectomy

Exclusion Criteria:

* children

Where this trial is running

Roma

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post Operative Pain
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.