Examining knee pain after ACL surgery and graft harvest
The Impact of Bone-tendon-bone Graft Harvest and Biological Regeneration of Bone-tendon Defects on the Development of Donor Site Morbidity After Anterior Cruciate Ligament Reconstruction
This study is trying to see if the bone and tendon changes from ACL surgery can lead to knee pain later on for people who have had the surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Clinical Center of Vojvodina Academic / other |
| Locations | 1 site (Novi Sad) |
| Trial ID | NCT06030791 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between bone-tendinous defects resulting from bone-tendon-bone (BTB) graft harvest during ACL reconstruction and the subsequent development of anterior knee pain. Participants will undergo MRI scans at two intervals, 4 weeks and 1 year post-surgery, to assess the presence and healing of these defects. Additionally, the study will evaluate knee functionality through standardized tests and scores to correlate with the observed defects. Informed consent has been obtained from all participants prior to their inclusion.
Who should consider this trial
Good fit: Ideal candidates include hospitalized patients diagnosed with ACL rupture confirmed by MRI.
Not a fit: Patients with multiligament knee injuries, bilateral knee injuries, ACL re-ruptures, or postoperative infections may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of knee pain following ACL reconstruction.
How similar studies have performed: While similar studies have explored ACL reconstruction outcomes, this specific focus on bone-tendinous defects and knee pain is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Hospitalized patients * Diagnosed with ACL rupture based on medical history and clinical examination * Confirmed ACL rupture on MRI scans * A sufficient level of education to understand study procedures and be able to communicate with site personnel Exclusion Criteria: * Multiligament knee injuries * Both knees injuries * ACL re-rupture * Postoperative complications in the form of infection
Where this trial is running
Novi Sad
- University Clinical Center of Vojvodina — Novi Sad, Serbia (Recruiting)
Study contacts
- Study coordinator: Mirko Obradovic, MD
- Email: mirko127@gmail.com
- Phone: +381643653086
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.