Examining how THC affects men and women differently
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study II
This study is testing how vaporized THC affects men and women differently to see if their reactions vary based on gender.
Quick facts
| Phase | Phase 1 |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 55 Years |
| Sex | All |
| Sponsor | Yale University Academic / other |
| Locations | 1 site (West Haven, Connecticut) |
| Trial ID | NCT04704271 on ClinicalTrials.gov |
What this trial studies
This study aims to investigate the acute effects of vaporized THC on healthy individuals, focusing on gender differences in response. It will involve administering THC and a placebo to participants who have prior cannabis exposure, while assessing their physical and mental health. The research seeks to understand the underlying mechanisms that contribute to any observed differences between men and women in their reactions to THC.
Who should consider this trial
Good fit: Ideal candidates are healthy individuals with at least one prior exposure to cannabis.
Not a fit: Patients who are cannabis naïve or experiencing major stressors may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more personalized cannabis treatments based on gender-specific responses.
How similar studies have performed: While there is ongoing research into the effects of cannabinoids, this specific focus on gender differences is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * At least one lifetime exposure to cannabis * Good physical and mental health Exclusion Criteria: * Cannabis naïve individuals * Major current or recent stressors
Where this trial is running
West Haven, Connecticut
- Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine — West Haven, Connecticut, United States (Recruiting)
Study contacts
- Study coordinator: Carly Hewes, BS
- Email: carly.hewes@yale.edu
- Phone: 2039325711
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.