Examining how physical activity affects Postural Orthostatic Tachycardia Syndrome

The Effect of Physical Activity on Postural Orthostatic Tachycardia Syndrome

Not applicable Interventional Lund University · NCT05554107

This study is testing if a structured exercise program can help people with Postural Orthostatic Tachycardia Syndrome feel better over 16 weeks.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorLund University Academic / other
Locations1 site (Malmö)
Trial IDNCT05554107 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of a structured physical activity program on patients diagnosed with Postural Orthostatic Tachycardia Syndrome (POTS). A total of 200 participants will be randomized into two groups, with each group undergoing a 16-week training program designed to improve their symptoms. The program includes supervised exercise sessions tailored to the severity of each patient's condition. Participants will also complete various questionnaires and undergo orthostatic tests to assess their health status before and after the intervention.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with POTS who are willing to participate and provide informed consent.

Not a fit: Patients with myalgic encephalomyelitis will not benefit from this study as they are excluded from participation.

Why it matters

Potential benefit: If successful, this study could provide a new, effective treatment approach for managing symptoms of POTS through physical activity.

How similar studies have performed: While physical activity is recommended in guidelines for POTS, this specific approach is novel and has not been extensively tested in clinical settings.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with POTS who have given written informed consent for participation in the study.

Exclusion Criteria:

* Patients with myalgic encephalomyelitis are excluded from the study.

Where this trial is running

Malmö

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions POTS - Postural Orthostatic Tachycardia SyndromeExercisePOTSTraining programmeTreatmentOrthostatic intolerance
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.