Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Examining how physical activity affects Postural Orthostatic Tachycardia Syndrome

Official title: The Effect of Physical Activity on Postural Orthostatic Tachycardia Syndrome

Run by Lund University · NCT05554107 · Data updated 2026-11-12

This study is testing if a structured exercise program can help people with Postural Orthostatic Tachycardia Syndrome feel better over 16 weeks.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorLund University
Academic / other
Locations1 site (Malmö)
StatusRecruiting
StartedNovember 2, 2022
Main results expectedMarch 2028
Study endsOctober 2028
Registry record updatedSeptember 3, 2026
Trial IDNCT05554107 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals diagnosed with POTS who are willing to participate and provide informed consent.

Probably not a fit

Patients with myalgic encephalomyelitis will not benefit from this study as they are excluded from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of a structured physical activity program on patients diagnosed with Postural Orthostatic Tachycardia Syndrome (POTS). A total of 200 participants will be randomized into two groups, with each group undergoing a 16-week training program designed to improve their symptoms. The program includes supervised exercise sessions tailored to the severity of each patient's condition. Participants will also complete various questionnaires and undergo orthostatic tests to assess their health status before and after the intervention.

Why it matters

Potential benefit: If successful, this study could provide a new, effective treatment approach for managing symptoms of POTS through physical activity.

How similar studies have gone: While physical activity is recommended in guidelines for POTS, this specific approach is novel and has not been extensively tested in clinical settings.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with POTS who have given written informed consent for participation in the study.

Exclusion Criteria:

* Patients with myalgic encephalomyelitis are excluded from the study.

Where it's running

  • Skånes Universitetssjukhus Malmö, Department of Cardiology
    Malmö, Sweden
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.