Examining how physical activity affects brain health through the glymphatic system

Physical Activity, Sleep and Brain Health Based on the Glymphatic System

Observational University of Valencia · NCT06378515

This study tests how exercise affects brain health in young adults by looking at changes in brain fluid movement during a workout.

Quick facts

Study typeObservational
Enrollment77 (estimated)
Ages18 Years to 40 Years
SexAll
SponsorUniversity of Valencia Academic / other
Locations1 site (Valencia)
Trial IDNCT06378515 on ClinicalTrials.gov

What this trial studies

This observational study investigates the relationship between physical activity and brain health in young adults by analyzing neurohydrodynamics and glymphatic activity. Participants will engage in a short exercise routine while wearing a Glymphometer, a device that monitors brain fluid dynamics. The study aims to collect data at two different times: before and during the exercise to assess changes in glymphatic function. The findings could provide insights into the role of lifestyle factors in preventing neurological diseases.

Who should consider this trial

Good fit: Ideal candidates for this study are university students who are enrolled in a bachelor's degree program and can provide informed consent.

Not a fit: Patients under 18 years old or those with cognitive or sensory difficulties may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved strategies for maintaining brain health and preventing neurodegenerative diseases through lifestyle modifications.

How similar studies have performed: While the glymphatic system is a relatively new area of research, similar studies have shown promising results in understanding brain health and the impact of physical activity.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Students enrolled in a bachelor's degree from one of the universities participating in the study.
* Students who consent to participate in the study indicating that they have been informed of all relevant aspects of the study.

Exclusion Criteria:

* Students under the age of 18.
* Students with cognitive or sensory difficulties or with insufficient command of the language that, in the opinion of the recruiting professional, makes it difficult to understand the questions raised in the surveys, scales or instruments used in the study.
* Who are participating at the time of recruitment in a clinical trial or experimental study. Participation in observational studies will not be an exclusion criterion

Where this trial is running

Valencia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Brain Diseasesglympathic systembrain healthphysical activityneurohydrodynamics
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.