Examining how infants of depressed mothers respond to emotional faces

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how infants of mothers with postpartum major depression exhibit attentional biases towards different emotional facial expressions. Infants will participate in a computer-based task while their gaze is tracked, and they will also engage in standardized interaction tasks with their mothers. The study aims to understand the role of infant arousal in developing these biases, comparing infants of depressed mothers to those of non-depressed mothers. The research will involve observing infant behavior in both free play and structured emotional contexts.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The high-risk group (n = 150) will consist of women with at least one episode of MDD since their baby's birth.
* To qualify for the low-risk group (n = 75), women cannot have a history of any depressive disorder or any current psychiatric diagnoses.
* Infants will be required to be singleton children born full-term (\> 37 weeks) and normal weight (\> 2,500 grams) with no birth complications or health problems to avoid medical complications contributing to infants' attention, reactivity, and regulation measures.
* The two groups will be matched on demographic factors (e.g., age, race/ethnicity, income).

Exclusion Criteria:

* Additional exclusion criteria are diagnoses of alcohol or substance use disorders currently or at any point during pregnancy, or lifetime history of bipolar or psychotic disorders.

Where it's running

• Binghamton University
  Binghamton, New York, United States Recruiting

Study contacts

• Study coordinator: Brandon E Gibb, Ph.D.
• Email: bgibb@binghamton.edu
• Phone: 607-777-2511

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.