Examining how different processed plant-based proteins affect gut health and metabolism
The Impact of Plant-Based Protein-rich Food Products With Varying Degree of Processing on the Human Gut Microbiome Composition and Human Metabolome
This study is testing how different types of processed plant-based proteins affect gut health and metabolism in healthy people.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 38 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | University of Turku Academic / other |
| Locations | 1 site (Turku) |
| Trial ID | NCT05885750 on ClinicalTrials.gov |
What this trial studies
This clinical intervention investigates the effects of various plant-based protein-rich food products, which differ in their level of processing, on the human gut microbiome and metabolism. The study will involve 38 healthy participants who will consume unprocessed, mildly processed, and heavily refined plant protein products. By assessing changes in gut microbiome composition and metabolic function, the research aims to clarify the nutritional quality of these food products. The findings could provide insights into how processing affects the health benefits associated with plant-based diets.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged 18-65 with a BMI between 18.5 and 27.
Not a fit: Patients with chronic diseases requiring continuous medication or those on gluten-free or vegan diets may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify the healthiest forms of plant-based proteins, guiding dietary choices for better gut health and metabolism.
How similar studies have performed: While there is limited research on the specific impacts of processed plant protein products, studies on plant-based diets have shown significant health benefits, suggesting potential for success in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Willingness to participate * 18-65-years olf * BMI 18.5-27 kg/m2 Exclusion Criteria: * Chronic disease with continuous medication * Antibiotic use in the past 6 months * Active smoker * Gluten-free or vegan diet * Pregnancy, lactation * Abnormal thyroid, liver, or kidney function * Low hemoglobin
Where this trial is running
Turku
- Food Sciences Unit, Department of Life Technologies, Faculty of Technology, University of Turku — Turku, Finland (Recruiting)
Study contacts
- Principal investigator: Kati Hanhineva, PhD — University of Turku
- Study coordinator: Veera Houttu, PhD
- Email: veera.houttu@utu.fi
- Phone: +358504627287
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.