Examining health impacts of past sports injuries and inactivity
Official title: Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health
Run by Marquette University · NCT05344001 · Data updated 2026-11-12
This study is trying to see how past sports injuries and being inactive affect the long-term health of former athletes compared to non-athletes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 64 Years |
| Sex | All |
| Enrollment | 450 (estimated) |
| Sponsor | Marquette University Academic / other |
| Locations | 1 site (Milwaukee, Wisconsin) |
| Status | Recruiting |
| Started | April 18, 2022 |
| Main results expected | August 2026 |
| Study ends | August 2027 |
| Registry record updated | February 25, 2026 |
| Trial ID | NCT05344001 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include current or former collegiate varsity athletes aged 18-25 or 40-64, as well as non-athlete controls within the same age ranges.
✕Probably not a fit
Patients with neurologic or degenerative diseases that impair function, those who are pregnant, or individuals with lower extremity joint replacements will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the long-term health outcomes of former competitive athletes, particularly focusing on those with prior knee injuries, compared to non-athlete controls. It aims to assess various health indicators, including strength, function, physical activity levels, dietary patterns, and cardiometabolic health among participants aged 18-25 and 40-64. The study will also explore how sedentary behavior and physical activity patterns differ between current athletes and non-athletes, as well as track changes in these variables over time. The overarching goal is to understand how prior injuries and inactivity contribute to poor health in midlife.
Why it matters
Potential benefit: If successful, this study could provide insights into how to improve long-term health outcomes for former athletes and inform interventions to mitigate risks associated with past injuries and sedentary behavior.
How similar studies have gone: While this study explores a specific aspect of health in former athletes, similar studies have shown that understanding the impact of injuries and physical activity on long-term health can lead to meaningful insights and interventions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Please see cohorts for specific inclusion/exclusion criteria Inclusion Criteria: * Age 18-25 years OR age 40-64 years * Current or former collegiate varsity athlete OR non-athlete control Exclusion Criteria: * Neurologic (e.g., stroke, Parkinson's) and/or degenerative disease that impairs function * Pregnancy * Lower extremity joint replacement (e.g., hip or knee replacement)
Where it's running
-
Marquette University
Milwaukee, Wisconsin, United States Recruiting
Study contacts
- Principal investigator: Jacob J. Capin, DPT, PhD, MS — Marquette University
- Study coordinator: Jacob J. Capin, DPT, PhD, MS
- Email: jacob.capin@marquette.edu
- Phone: 414-288-7865
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.