Examining factors affecting fitness in patients who had the Fontan procedure

Pulmonary Determinants of Cardiorespiratory Fitness in Patients With Fontan Procedure

Observational Hacettepe University · NCT05684562

This study looks at how lung function affects fitness in people who have had the Fontan procedure for congenital heart disease.

Quick facts

Study typeObservational
Enrollment78 (estimated)
Ages8 Years to 55 Years
SexAll
SponsorHacettepe University Academic / other
Locations1 site (Ankara)
Trial IDNCT05684562 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the pulmonary determinants of cardiorespiratory fitness in patients who have undergone the Fontan procedure for congenital heart disease. It will involve the collection of medical records and routine evaluations, including physical examinations and various tests such as cardiopulmonary exercise tests and pulmonary function tests. No additional interventions or changes in treatment will be made as part of this study, focusing solely on existing patient data and routine assessments. The goal is to better understand the relationship between pulmonary function and fitness in this specific patient population.

Who should consider this trial

Good fit: Ideal candidates include individuals aged 8-55 who have undergone the Fontan operation and are clinically stable.

Not a fit: Patients with neurological, genetic, or orthopedic issues that prevent testing may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights that improve the management and rehabilitation of Fontan patients, enhancing their quality of life.

How similar studies have performed: While similar studies have explored aspects of fitness in congenital heart disease, this specific focus on pulmonary determinants in Fontan patients is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Fontan Group Inclusion Criteria:

* Be between 8-55 years old
* Having undergone a Fontan operation
* Clinical stability of the patients (preserved ventricular function)
* No change in ongoing drug therapy that adversely affects clinical stability
* At least 1 year after the operation

Fontan Group Exclusion Criteria:

* Neurological and/or genetic musculoskeletal disease
* Having orthopedic and cognitive problems that prevent testing
* The patient's and/or family's unwillingness to participate in the study

Control Group Inclusion Criteria:

* Not have cardiovascular, neurological, and/or genetic musculoskeletal disease
* Not having orthopedic and cognitive problems that prevent testing
* The patient's and/or family's willingness to participate in the study

Where this trial is running

Ankara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Fontan ProcedureCongenital Heart Disease
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.