Examining energy use in cardiac arrest patients undergoing temperature management

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze resting energy expenditure and substrate consumption in cardiac arrest patients who are undergoing targeted temperature management (TTM) in an intensive care unit. A total of 40 patients will be enrolled after successful cardiopulmonary resuscitation and will be divided into two groups based on their core body temperature: one group at 33 °C and the other at 36 °C. Baseline data will be collected, and patients will receive parenteral nutrition after a fasting period to assess their energy expenditure at various time points during their treatment. The study seeks to provide insights into the metabolic needs of these patients during critical care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Be admitted to the emergency department of Beijing Chao-yang Hospital, Capital Medical University;
* Successfully resuscitated, and are unconscious after restoration of spontaneous circulation (ROSC);
* Be admitted to the intensive care unit (ICU) for advanced life support such as endotracheal intubation after restoration of spontaneous circulation (ROSC);
* Accepted target temperature management (TTM) therapy after restoration of spontaneous circulation (ROSC);

Exclusion Criteria:

* Age \> 18 years old；
* Incomplete clinical data and loss of follow-up;
* Traumatic brain injury or cerebrovascular accident revealed by computed tomography (CT)；
* Severe metabolic abnormalities are known: cachexia, thyroid dysfunction, and cancer；
* Indirect calorimetry measurement is not possible such as sustained oxygen concentration \> 70%；
* There were no signs of resuscitation at the time of admission；

Where it's running

• Beijing chao-yang Hospital, Capital Medical University
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Ziren Tang, MD
• Email: tangziren1970@163.com
• Phone: 010-85231530

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.