Examining discarded materials from IVF cycles to understand treatment outcomes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects and analyzes various discarded materials from in vitro fertilization (IVF) treatment cycles, such as immature oocytes and abnormal embryos, to identify potential indicators of successful outcomes or cycle failures. The study employs next-generation sequencing for DNA and RNA analysis, along with transcriptome profiling and protein analysis, to explore the underlying reasons for IVF success or failure. The goal is to develop a non-invasive testing method for assessing embryo quality and improving implantation potential, ultimately enhancing clinical outcomes in IVF treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients attending the Assisted Reproductive Technology (ART) Unit of the Chinese University of Hong Kong for ART treatment.
* Participant able to give voluntary, written, informed consent to participate in the study.

Exclusion Criteria:

* Patient using donor gamete in IVF treatment
* Patient refuses to join and failed to giving consent for any reasons

Where it's running

• The Chinese University of Hong Kong and Prince of Wales Hospital
  Hong Kong, Hong Kong Recruiting

Study contacts

• Principal investigator: Yiu Leung D Chan, DPhil — Cuhk
• Study coordinator: Yiu Leung D Chan, DPhil
• Email: drdcyl16@cuhk.edu.hk
• Phone: (852) 3505 3199

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pentoxifylline to improve uterine lining and frozen embryo transfer outcomes

  This trial sees if giving pentoxifylline alongside standard estradiol helps women with good-quality day‑5 frozen embryos get a thicker uterine lining and better frozen embryo transfer success.

  Recruiting Phase 3 Beni-Suef University · Banī Suwayf, Beni Suweif Governorate · NCT07499817

• Aromatherapy to support mental health in women undergoing IVF

  This will test whether inhaling lavender oil twice daily can reduce anxiety, stress, and depression and improve quality of life for women awaiting IVF.

  Recruiting Federal University of Minas Gerais · Belo Horizonte, Minas Gerais · NCT07480668

• In vitro maturation of human eggs for fertility treatment

  This study is testing a new way to help women with fertility issues by maturing their eggs in the lab with fewer hormones to see if it makes treatment easier and safer.

  Recruiting Colorado Center for Reproductive Medicine · Lone Tree, Colorado · NCT06633120

• Comparing immediate and postponed embryo transfer for infertility treatment

  This study is testing whether transferring an embryo right after egg retrieval is just as effective as waiting to transfer it later for helping people with infertility have a baby.

  Recruiting Copenhagen University Hospital, Rigshospitalet · Copenhagen · NCT06304792

• Selecting sperm for gender-specific offspring

  This study is testing a new way to choose sperm based on whether it carries an X or Y chromosome to help couples undergoing infertility treatment have a baby of a specific gender.

  Recruiting Weill Medical College of Cornell University · New York, New York · NCT05500573

• Long-term follow-up for patients using preimplantation genetic testing

  This study is trying to learn about the long-term experiences and outcomes of people who have used preimplantation genetic testing during IVF to help improve care in reproductive genetics.

  Recruiting Genomic Prediction Inc. · North Brunswick, New Jersey · NCT04477863

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.