Examining differences in cardiac surgery outcomes between men and women
Official title: SEx-specific Differences in Cardiac Surgery Patients (SECS). A Retrospective Registration and Evaluation of Characteristics and Perioperative Management of Cardiac Surgery Patients
Run by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · NCT06554925 · Data updated 2026-11-12
This study looks at how men and women experience cardiac surgery differently to see if there are specific factors that can help improve recovery for women.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Academic / other |
| Locations | 1 site (Amsterdam, North Holland) |
| Status | Recruiting |
| Started | March 1, 2022 |
| Main results expected | March 1, 2030 |
| Study ends | March 1, 2031 |
| Registry record updated | August 15, 2024 |
| Trial ID | NCT06554925 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years who have undergone cardiac surgery at the specified institution.
✕Probably not a fit
Patients who have not undergone cardiac surgery or are under 18 years old may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the differences in perioperative factors between female and male patients undergoing cardiac surgery. It will analyze various parameters such as body weight adaptation, medical history, pharmacokinetics, and outcomes related to morbidity and mortality at short-term and long-term intervals. The study seeks to establish a database of these perioperative parameters to identify factors that may adversely affect recovery in females, with the goal of improving their surgical outcomes. By focusing on sex-specific differences, the research aims to enhance perioperative care pathways tailored for female patients.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery and reduced complications for female patients undergoing cardiac surgery.
How similar studies have gone: While there have been studies on preoperative cardiovascular differences, this specific focus on female-specific perioperative care in cardiac surgery is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients \> 18 years * All patients who underwent cardiac surgery from 1 January 1998 in the AUMC, location VUmc, until 1 June 2021. Exclusion Criteria: * None
Where it's running
-
Academic Medical Center
Amsterdam, North Holland, Netherlands Recruiting
Study contacts
- Principal investigator: Markus W Hollmann, Professor — Anesthesiology and Pain Medicine, Amsterdam Medical Center
- Study coordinator: Jennifer S Breel, MSc
- Email: j.s.breel@amsterdamumc.nl
- Phone: +31610019257
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.