Examining differences in cardiac surgery outcomes between men and women
SEx-specific Differences in Cardiac Surgery Patients (SECS). A Retrospective Registration and Evaluation of Characteristics and Perioperative Management of Cardiac Surgery Patients
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · NCT06554925
This study looks at how men and women experience cardiac surgery differently to see if there are specific factors that can help improve recovery for women.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (other) |
| Locations | 1 site (Amsterdam, North Holland) |
| Trial ID | NCT06554925 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the differences in perioperative factors between female and male patients undergoing cardiac surgery. It will analyze various parameters such as body weight adaptation, medical history, pharmacokinetics, and outcomes related to morbidity and mortality at short-term and long-term intervals. The study seeks to establish a database of these perioperative parameters to identify factors that may adversely affect recovery in females, with the goal of improving their surgical outcomes. By focusing on sex-specific differences, the research aims to enhance perioperative care pathways tailored for female patients.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years who have undergone cardiac surgery at the specified institution.
Not a fit: Patients who have not undergone cardiac surgery or are under 18 years old may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery and reduced complications for female patients undergoing cardiac surgery.
How similar studies have performed: While there have been studies on preoperative cardiovascular differences, this specific focus on female-specific perioperative care in cardiac surgery is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients \> 18 years * All patients who underwent cardiac surgery from 1 January 1998 in the AUMC, location VUmc, until 1 June 2021. Exclusion Criteria: * None
Where this trial is running
Amsterdam, North Holland
- Academic Medical Center — Amsterdam, North Holland, Netherlands (RECRUITING)
Study contacts
- Principal investigator: Markus W Hollmann, Professor — Anesthesiology and Pain Medicine, Amsterdam Medical Center
- Study coordinator: Jennifer S Breel, MSc
- Email: j.s.breel@amsterdamumc.nl
- Phone: +31610019257
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Female, Male, Surgery, Cardiac, anesthesia, sex-specific differences, cardiac surgery, care pathways