Examining changes in eye blood vessels after cataract surgery
Changes of Macular Vasculature After Uncomplicated Phacoemulsification Surgery Using Optical Coherence Tomography Angiography
This study looks at how cataract surgery affects blood vessels in the eyes of people with and without diabetic retinopathy to see if there are any changes in their eye health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 30 Years to 70 Years |
| Sex | All |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, El-Garbeia) |
| Trial ID | NCT04594603 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the vascular changes in the macula following uncomplicated phacoemulsification surgery using Optical Coherence Tomography Angiography (OCTA). It involves a prospective analysis of 30 patients with cataracts, divided into two groups: those without diabetic retinopathy and those with diabetic retinopathy. Comprehensive ophthalmologic examinations and high-quality OCTA imaging will be conducted to evaluate the superficial and deep capillary retinal plexus. The study will analyze vessel density as an indicator of macular and papillary perfusion.
Who should consider this trial
Good fit: Ideal candidates include patients with senile or complicated cataracts, specifically those with or without diabetic retinopathy.
Not a fit: Patients with a history of ocular trauma, previous intraocular surgery, or those with significant complications during surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of vascular changes in diabetic patients post-surgery, potentially leading to improved management of diabetic retinopathy.
How similar studies have performed: While there have been studies on OCTA in diabetic retinopathy, this specific approach to assess changes post-cataract surgery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * - Presence of a nuclear, cortical cataract or complicated cataract due to diabetic mellitus * Intraocular pressure (IOP) of 21 mm Hg or lower * Axial length (AL) between 20.0 mm and 25.0 mm. Exclusion Criteria: * Eyes with an AL longer than 25.0 mm or shorter than 20.0 mm, * IOP higher than 21 mm Hg, * History of ocular trauma or intraocular surgery, or any abnormal intraocular findings * Poor OCT-A images because of severe cataracts or unstable fixation * Any signs of intraoperative or postoperative complications
Where this trial is running
Tanta, El-Garbeia
- Tanta University Hospital — Tanta, El-Garbeia, Egypt (Recruiting)
Study contacts
- Study coordinator: Dina SM Tadros, MD
- Email: dinasabry@rocketmail.com
- Phone: 00201224093354
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.