Clinical trial Recruiting at 1 site Observational Ages 18 to 100 Women only

Examining cardiovascular and lymphatic systems in women with Turner Syndrome

Official title: Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome

Run by University of Aarhus · NCT06325618 · Data updated 2026-11-12

This study is testing how the heart and lymphatic systems work in women with Turner Syndrome to see if there are any problems that could lead to health issues.

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Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexWomen only
Enrollment150 (estimated)
SponsorUniversity of Aarhus
Academic / other
Locations1 site (Aarhus N)
StatusRecruiting
StartedJanuary 8, 2024
Main results expectedAugust 2027
Study endsAugust 2027
Registry record updatedMarch 22, 2024
Trial IDNCT06325618 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult women with a karyotype verified diagnosis of Turner Syndrome.

Probably not a fit

Patients who are pregnant or have contraindications for MRI will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the cardiovascular and lymphatic systems in women diagnosed with Turner Syndrome (TS) by conducting a fifth study visit for participants who have previously been examined over a 19-year period. The study will include healthy age-matched females as controls in a 2:1 ratio. Researchers will investigate potential defects and dysfunctions in these systems to understand the complications associated with TS, including lymphedema and cardiovascular diseases. The study will also explore the relationship between low-grade inflammation and vascular structure alterations in TS patients.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of life-threatening complications associated with Turner Syndrome.

How similar studies have gone: While there have been studies on Turner Syndrome, this specific approach examining the interplay between lymphatic and cardiovascular systems in this population is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Turner Syndrome

Exclusion Criteria:

* pregnancy
* contraindications for MRI

Where it's running

  • Aarhus University Hospital
    Aarhus N, Denmark
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.