Examining cardiovascular and lymphatic systems in women with Turner Syndrome
Official title: Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome
Run by University of Aarhus · NCT06325618 · Data updated 2026-11-12
This study is testing how the heart and lymphatic systems work in women with Turner Syndrome to see if there are any problems that could lead to health issues.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | Women only |
| Enrollment | 150 (estimated) |
| Sponsor | University of Aarhus Academic / other |
| Locations | 1 site (Aarhus N) |
| Status | Recruiting |
| Started | January 8, 2024 |
| Main results expected | August 2027 |
| Study ends | August 2027 |
| Registry record updated | March 22, 2024 |
| Trial ID | NCT06325618 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adult women with a karyotype verified diagnosis of Turner Syndrome.
✕Probably not a fit
Patients who are pregnant or have contraindications for MRI will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the cardiovascular and lymphatic systems in women diagnosed with Turner Syndrome (TS) by conducting a fifth study visit for participants who have previously been examined over a 19-year period. The study will include healthy age-matched females as controls in a 2:1 ratio. Researchers will investigate potential defects and dysfunctions in these systems to understand the complications associated with TS, including lymphedema and cardiovascular diseases. The study will also explore the relationship between low-grade inflammation and vascular structure alterations in TS patients.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of life-threatening complications associated with Turner Syndrome.
How similar studies have gone: While there have been studies on Turner Syndrome, this specific approach examining the interplay between lymphatic and cardiovascular systems in this population is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Turner Syndrome Exclusion Criteria: * pregnancy * contraindications for MRI
Where it's running
-
Aarhus University Hospital
Aarhus N, Denmark Recruiting
Study contacts
- Study coordinator: Line Balsby, MD
- Email: libals@clin.au.dk
- Phone: +4520461203
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.