Examining brain changes in veterans with chronic pain using spinal cord stimulation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how spinal cord stimulation (SCS) affects brain structure and function in veterans suffering from chronic neuropathic pain. Utilizing non-invasive neuroimaging techniques, specifically resting state Near Infrared Spectroscopy and Electroencephalography (rs-fNIRS/EEG), the study will enroll two cohorts: those new to SCS and long-term users. The goal is to identify neurophysiological signatures associated with pain relief, which may enhance understanding of SCS efficacy and help predict patient responses to treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years of age and a US veteran
* Diagnosis of chronic neuropathic pain.
* Current patient at Cleveland VA Medical Center receiving care via Pain Medicine Center.
* Current user of tonic parasthesia-based SCS (pain relief 50% according to NPRS) or undergoing trial SCS period as part of clinical care.
* Able to provide informed consent.
* Medically and psychologically stable.

Exclusion Criteria:

* Metal in the skull or deformity of the skull
* Pregnancy or pregnancy planning during the study period.
* Unable to provide informed consent.

Where it's running

• Louis Stokes VA Medical Center, Cleveland, OH
  Cleveland, Ohio, United States Recruiting

Study contacts

• Principal investigator: Svetlana Pundik, MD — Louis Stokes VA Medical Center, Cleveland, OH
• Study coordinator: Cheryl Dudek
• Email: cheryl.dudek@va.gov
• Phone: (216) 679-3800

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.