Examining brain activity in children with acute concussion

Interhemispheric Anterior Delta Desynchronization in Children Who Present to the Emergency Department With Acute Concussion: A Proof of Concept Study

Observational Rambam Health Care Campus · NCT02916108

This study looks at brain activity in kids aged 11-18 who have just had a concussion to see how it differs from healthy kids with other injuries, hoping to improve how we understand and treat concussions.

Quick facts

Study typeObservational
Enrollment60 (estimated)
Ages11 Years to 18 Years
SexAll
SponsorRambam Health Care Campus Academic / other
Locations1 site (Haifa)
Trial IDNCT02916108 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the brain activity patterns in children aged 11-18 who present to the emergency department with acute concussion. By utilizing EEG readings, the study seeks to identify interhemispheric anterior delta desynchronization, which may provide insights into the severity and management of concussion symptoms. The study will also include a control group of healthy children with isolated limb injuries to compare findings. The goal is to enhance the understanding of concussion and improve diagnostic accuracy.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 11-18 years diagnosed with acute concussion.

Not a fit: Patients who are nonverbal or non-cooperative will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more accurate diagnoses and better management strategies for children suffering from concussions.

How similar studies have performed: While there have been studies on concussion, this specific approach using EEG for acute concussion assessment is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Study group will include children aged 11-18 years with diagnosis of acute concussion based on the RPSQ. (Eisenberg et al., 2013; Harmon et al., 2013)
* Controls will be healthy children who will be admitted to the ED due to an isolated limb injury such as laceration, contusion or fracture and are not painful. Nonverbal or non-cooperative children will be excluded from the study.

Exclusion Criteria:

* Nonverbal or non-cooperative children.
* Lack of inform consent.

Where this trial is running

Haifa

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Concussion, Mild Traumatic Brain InjuryConcussionMild traumatic brain injuryEEG
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.