Examining bone development in children with type-1 diabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Canadian Bone Strength Development Study aims to investigate the differences in bone development between children with type-1 diabetes (T1D) and those without. This observational study will involve 204 children, who will participate in four annual laboratory visits where various measurements related to bone strength, muscle strength, nutrition, and physical activity will be taken. The study will analyze how bone growth trajectories differ based on sex and the impact of body composition and physical activity on these differences. The findings could provide insights into the skeletal health of children with T1D during critical growth periods.

Why it matters

Who can join: the full rules

Children with Type-I Diabetes:

Inclusion Criteria

* Females: 10-11 years old.
* Males: 11 - 12 years old.
* Diagnosed with type-1 diabetes for at least 6 months.
* Capacity to give informed consent (patient and parent/guardian). Children with the capacity to give assent will do so in addition to parental consent.

Exclusion Criteria

* Consuming any medications or have additional illnesses associated with bone health, osteoporosis (including renal disease, celiac disease, hypogonadism, hyperthyroidism) or altered physical growth (precocious puberty).
* Have gone through adolescent growth spurt at study entry.

Control Group (Typically Developing Children):

Inclusion Criteria

* Females: 10-11 years old.
* Males: 11 - 12 years old.
* Capacity to give informed consent (patient and parent/guardian). Children with the capacity to give assent will do so in addition to parental consent.

Exclusion Criteria

* Have an illness or are taking medications influencing bone health or physical growth.
* Evidence of pathologic low trauma or vertebral fracture(s).
* Have gone through adolescent growth spurt at study entry.

Where it's running

• University of Saskatchewan
  Saskatoon, Saskatchewan, Canada Recruiting

Study contacts

• Study coordinator: Saija Kontulainen, PhD
• Email: saija.kontulainen@usask.ca
• Phone: (306)966-1077

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.