Examining blood markers in patients with and without intestinal polyps
Proof-of-concept Study of Blood Markers of Tumor Dissemination in Patients with Versus Without Intestinal Polyps
This study looks at blood samples from people with and without intestinal polyps to see if certain markers can help improve follow-up care and treatment for colorectal cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de Nīmes Academic / other |
| Locations | 1 site (Nîmes) |
| Trial ID | NCT05648240 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate whether tumor cells can disseminate and if circulating factors are secreted by intestinal polyps in patients. By analyzing blood samples from individuals undergoing colonoscopy, the researchers hope to identify potential biomarkers that could enhance patient follow-up and inform targeted treatment strategies. The study focuses on patients with intestinal polyps and compares them to those without, providing insights into colorectal cancer and neoplasm metastasis.
Who should consider this trial
Good fit: Ideal candidates include patients undergoing colonoscopy who have intestinal polyps or are being monitored for colorectal health.
Not a fit: Patients with a history of proven cancerous disease or chronic inflammatory bowel disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring and treatment strategies for patients at risk of colorectal cancer.
How similar studies have performed: While this approach is innovative, similar studies exploring blood biomarkers in cancer detection have shown promise, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient to be examined by colonoscopy * The patient must be a member or beneficiary of a health insurance plan Exclusion Criteria: * The subject is participating in a category 1 interventional study, or is in a period of exclusion determined by a previous study * The subject signals their opposition to participate in the study * It is impossible to give the subject informed information * The patient is under safeguard of justice or state guardianship * Patient pregnant or breastfeeding * History of proven cancerous disease * Patient followed for a chronic inflammatory bowel disease
Where this trial is running
Nîmes
- CHU de Nîmes — Nîmes, France (Recruiting)
Study contacts
- Principal investigator: Jean-François BOURGAUX — CHU de Nimes
- Study coordinator: Jean-François BOURGAUX
- Email: jean.francois.bourgaux@chu-nimes.fr
- Phone: 04.66.68.81.85
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.