Examining blood loss in women with preeclampsia
Does Preeclampsia Affect Blood Loss During a Caesarean Procedure
This study is trying to see how much blood loss happens in women with preeclampsia compared to healthy pregnant women to better understand the risks of bleeding in both groups.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | University of Zurich Academic / other |
| Locations | 1 site (Zurich) |
| Trial ID | NCT04777097 on ClinicalTrials.gov |
What this trial studies
This observational study investigates blood loss in patients with preeclampsia by utilizing mathematical formulas to quantify and compare blood loss between preeclamptic patients and healthy pregnant women. The research aims to understand the correlation between blood loss and coagulation status, particularly focusing on the risks associated with impaired coagulation in preeclampsia. By analyzing blood samples and clinical data, the study seeks to enhance the assessment of bleeding risks in both preeclamptic and healthy pregnant populations.
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant women undergoing elective or urgent caesarean sections who can provide written informed consent.
Not a fit: Patients who may not benefit from this study include those with emergency caesarean sections or existing hematological disorders affecting platelet counts.
Why it matters
Potential benefit: If successful, this study could improve the management of bleeding risks in pregnant women, particularly those with preeclampsia.
How similar studies have performed: While this approach is innovative, similar studies have not been widely reported, indicating that this may be a novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Elective or urgent caesarean section * Written informed consent Exclusion Criteria: * Emergency caesarean section * Familial coagulation disorder * Hematological disorders that affect the platelet count, e.g. myelodysplastic syndrome (MDS) * Taking anticoagulants * Taking aspirin in the last 14 days * Use of NSARs in the last 24 hours
Where this trial is running
Zurich
- University Hospital Zurich, Institute for Anesthesiology — Zurich, Switzerland (Recruiting)
Study contacts
- Principal investigator: Marco P Zalunardo — Institut of Anesthesiology University Hospital Zurich
- Study coordinator: Marco P Zalunardo, Prof
- Email: marco.zalunardo@usz.ch
- Phone: +41442552695
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.