Examining B-catenin in skin cancer and similar lesions
Expression of B-catenin in Cutaneous Squamous Cell Carcinoma and Its Mimickers
This study is trying to see if looking at a protein called B-catenin can help doctors tell cutaneous squamous cell carcinoma apart from other similar skin issues.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06536946 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the role of B-catenin in differentiating cutaneous squamous cell carcinoma from other similar skin lesions. It focuses on the expression of B-catenin using immunohistochemical staining techniques. The study aims to improve the accuracy of diagnosing cutaneous squamous cell carcinoma, which can often be confused with other conditions. By analyzing tissue samples, researchers hope to clarify the diagnostic criteria for this common form of skin cancer.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with tissue samples from diagnosed cases of cutaneous squamous cell carcinoma or its mimickers.
Not a fit: Patients with insufficient or necrotic tissue samples will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate diagnoses of cutaneous squamous cell carcinoma, improving treatment outcomes for patients.
How similar studies have performed: While the specific role of B-catenin in this context may be novel, similar studies have shown that immunohistochemical markers can significantly aid in the diagnosis of skin cancers.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * tissue blocks with sufficient materials Cases with sufficient data Exclusion Criteria: * tissue blocks with insufficient and necrotic materials. Casas with insufficient data
Where this trial is running
Sohag
- Sohag University hospital — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: Nermeen S Habeeb, Doctor
- Email: nermin.tharwat@med.sohag.edu.eg
- Phone: 01200496394
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.