Evaluation of a new blood culture system for diagnosing infections in West Africa
Diagnostic Evaluation Study of the BactInsight Blood Culture System in West-Africa
This study is testing a new blood culture system to see if it can help diagnose infections better in West Africa, where there aren't many labs available.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1347 (estimated) |
| Ages | 15 Years and up |
| Sex | All |
| Sponsor | Institute of Tropical Medicine, Belgium Academic / other |
| Locations | 2 sites (Boko and 1 other locations) |
| Trial ID | NCT05722184 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the BactInsight blood culture system, designed to improve the diagnosis of bloodstream infections (BSI) in low-resource settings (LRS) where traditional microbiology laboratories are scarce. The study aims to assess the effectiveness of this simplified, cost-effective, and robust blood culture system, which requires minimal training for laboratory staff. By enabling more widespread use of blood cultures, the study seeks to enhance the treatment of bacterial infections and reduce the overuse of antibiotics that contributes to antimicrobial resistance.
Who should consider this trial
Good fit: Ideal candidates include individuals with indications for blood culture sampling as part of standard clinical practice.
Not a fit: Patients who do not require blood culture sampling or are unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve the diagnosis and treatment of bacterial infections in low-resource settings.
How similar studies have performed: Other studies have shown promise in using simplified diagnostic systems in low-resource settings, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * With indications for blood culture sampling and for whom collection of a blood culture sample is part of standard clinical practice * Willing and able to provide written informed consent (assent for minors) Exclusion Criteria: * none
Where this trial is running
Boko and 1 other locations
- Hôpital Saint Jean de Dieu de Boko — Boko, Benin (Recruiting)
- Centre National Hospitalier et Universitaire Hubert Koutoukou MAGA — Cotonou, Benin (Recruiting)
Study contacts
- Principal investigator: Barbara Barbé — Instituut voor Tropische Geneeskunde
- Study coordinator: Liselotte Hardy, Dr.
- Email: lhardy@itg.be
- Phone: +32(0)32476693
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.