Evaluation and management of inflammatory and infectious diseases
Diagnosis and Management of Inflammatory and Infectious Diseases
This study is testing how to better diagnose and treat people with inflammatory and infectious diseases that don't fit into current treatment plans.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 3 Years to 100 Years |
| Sex | All |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Locations | 1 site (Bethesda, Maryland) |
| Trial ID | NCT00557726 on ClinicalTrials.gov |
What this trial studies
This protocol aims to evaluate patients with diagnosed or suspected inflammatory and infectious diseases that are not covered by existing protocols. Patients will be assessed for their conditions, and if a diagnosis is made, they may be referred to ongoing NIH protocols for further treatment. If no relevant protocol exists, participants will receive standard care either through external providers or within this protocol. The study also aims to collect clinical data and samples to enhance understanding of these diseases and support future research.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 3 years and older with known or suspected exposure to infection or symptoms of an infectious or inflammatory disease.
Not a fit: Patients who are pregnant or have conditions that may pose undue risk or make them unsuitable for participation will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the diagnosis and management of inflammatory and infectious diseases, leading to better patient outcomes.
How similar studies have performed: While this approach has been established since 1978, it serves as a foundational protocol for evaluating such diseases, indicating a long-standing commitment to this area of research.
Eligibility criteria
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: 1. Known or suspected exposure to infection, as determined by the Principal Investigator OR Presence of signs and symptoms of an infectious or inflammatory disease 2. Age range: 3 years of age and older. 3. NIAID/LIR investigator who has an interest in the patient s illness and is willing to serve as attending physician to supervise the patient's medical care at the NIH. 4. Primary physician outside the NIH 5. The patient or the patient's Legally Authorized Representative is capable of informed consent and signs the consent form. The consent form will be signed by parents or guardians of patients under the age of 18 EXCLUSION CRITERIA: 1. Pregnant. 2. Presence of conditions that, in the judgment of the investigator, may put the participant at undue risk or make them unsuitable for participation in the study.
Where this trial is running
Bethesda, Maryland
- National Institutes of Health Clinical Center — Bethesda, Maryland, United States (Recruiting)
Study contacts
- Principal investigator: Mary E Wright, M.D. — National Institute of Allergy and Infectious Diseases (NIAID)
- Study coordinator: Rosemary McConnell, R.N.
- Email: rosemary.mcconnell@nih.gov
- Phone: (301) 312-1235
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.