Evaluating wrist orthoses for managing carpal tunnel syndrome

Evaluation of a Conservative Treatment by Nocturnal Wrist Orthosis in the Non-surgical Management of Carpal Tunnel Syndrome

Not applicable Interventional Centre Hospitalier Saint Joseph Saint Luc de Lyon · NCT05483218

This study is testing two different types of wrist braces to see which one helps people with carpal tunnel syndrome feel better and recover more effectively without surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorCentre Hospitalier Saint Joseph Saint Luc de Lyon Academic / other
Locations5 sites (Bron and 4 other locations)
Trial IDNCT05483218 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of two types of nocturnal wrist orthoses in the non-surgical management of carpal tunnel syndrome. Patients diagnosed with the condition will be randomized into two groups, one receiving a simple rest orthosis and the other a global rest orthosis. The study aims to assess symptom reduction, comfort, compliance, and the impact on neurological and muscular recovery over a three-month period. Follow-up will include telephone interviews and consultations to monitor progress and functional outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 with unilateral or bilateral carpal tunnel syndrome who do not require surgical intervention.

Not a fit: Patients with severe carpal tunnel syndrome or those currently participating in other research protocols may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a non-invasive treatment option that effectively alleviates symptoms of carpal tunnel syndrome.

How similar studies have performed: Other studies have shown promise in using orthotic devices for similar conditions, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients over 18 years of age with unilateral or bilateral, idiopathic or secondary carpal tunnel syndrome, without surgical indication (EMG with myelin sensory signs without axonal involvement)
* signed consent
* Affiliation to social security

Exclusion Criteria:

* Patients with carpal tunnel syndrome with severity criteria
* Patient refusal
* Patient with disorders (psychological, behavioral) that may lead to poor compliance with the study treatment
* Presence of skin lesion in the area of the orthosis
* Current participation in another research protocol involving the human person

Where this trial is running

Bron and 4 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Carpal Tunnel Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.