Evaluating VSJ-110 for treating dry eye

A Four-Week, Double-Masked, Randomized, Placebo-Controlled, Phase 2, Evaluation of the Safety and Efficacy of VSJ-110 Ophthalmic Solution in the Treatment of Dry Eye

PHASE2 · Vanda Pharmaceuticals · NCT06296966

This study is testing a new treatment called VSJ-110 to see if it can help adults with dry eye feel better compared to a placebo.

Quick facts

PhasePHASE2
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorVanda Pharmaceuticals (industry)
Locations1 site (Andover, Massachusetts)
Trial IDNCT06296966 on ClinicalTrials.gov

What this trial studies

This study aims to assess the safety and efficacy of a new treatment called VSJ-110 compared to a placebo for individuals suffering from dry eye. Participants will be monitored for their response to the treatment and any potential side effects. The study will involve adults aged 18 and older who meet specific eligibility criteria and are willing to attend all required visits. The findings could provide valuable insights into a new therapeutic option for managing dry eye symptoms.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older experiencing symptoms of dry eye.

Not a fit: Patients currently using disallowed medications or those who do not meet the eligibility criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could offer a new effective option for patients suffering from dry eye.

How similar studies have performed: While this specific approach is being evaluated in this trial, similar studies have shown promise in developing new treatments for dry eye.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be at least 18 years of age of either gender and any race.
* Provide written informed consent and sign the HIPAA form.
* Be willing and able to follow all instructions and attend all study visits.

Exclusion Criteria:

* Use of any of the disallowed medications during the washout and study period.

Where this trial is running

Andover, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Dry Eye

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.