Evaluating visual rehabilitation's effects on anxiety and depression in patients with AMD

Evaluation of the Impact of Visual Rehabilitation on Anxiety and Depression Severity of Visually Impaired Patients with Advanced Age Related Macular Degeneration

Observational Fondazione G.B. Bietti, IRCCS · NCT06906003

This study is testing whether a visual rehabilitation program can help reduce anxiety and depression in people with advanced age-related macular degeneration.

Quick facts

Study typeObservational
Enrollment22 (estimated)
Ages55 Years and up
SexAll
SponsorFondazione G.B. Bietti, IRCCS Academic / other
Locations1 site (Rome, Italy)
Trial IDNCT06906003 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the impact of a visual rehabilitation program on anxiety and depression levels in visually impaired patients suffering from advanced age-related macular degeneration (AMD). Participants will undergo a series of assessments, including ophthalmological examinations and questionnaires measuring anxiety and depression. The study involves three visits: an initial screening, a 60-day rehabilitation program with group meetings, and a final evaluation to measure outcomes. The research is conducted at two locations in Rome, Italy.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 55 and older with moderate to severe visual impairment due to advanced non-exudative AMD.

Not a fit: Patients with visual impairment from other ocular diseases or those with mild visual impairment or total blindness may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the mental health and quality of life for visually impaired patients with AMD.

How similar studies have performed: Other studies have shown positive outcomes in visual rehabilitation programs for similar patient populations, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Subjects ≥ 55 years
2. Moderate and severe visual impairment (BCVA ≥1/10 and ≤2/10)
3. Diagnosis of advanced non-exudative age-related macular degeneration (AMD)
4. Informed consent freely granted and acquired before the start of the study
5. Ability to understand and willingness to follow the study instructions and procedures

Exclusion Criteria:

1. Visual impairment due to other ocular diseases
2. Mild visual impairment or partial or total blindness
3. Exudative age-related macular degeneration undergoing intravitreal drug treatment

Where this trial is running

Rome, Italy

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AMD - Age-Related Macular DegenerationAnxietyDepression Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.