Evaluating visual field detection methods in early glaucoma patients

Evaluation of Different Perimetric Grids to Detect Central Visual Field Defect in Glaucoma Patients with Reduce Ganglion Cell Layer Thickness Measured by Spectral Domain OCT.

Observational Fondazione G.B. Bietti, IRCCS · NCT06227611

This study is testing which of three different methods works best to find vision problems in people with early glaucoma.

Quick facts

Study typeObservational
Enrollment16 (estimated)
Ages18 Years and up
SexAll
SponsorFondazione G.B. Bietti, IRCCS Academic / other
Locations2 sites (Rome and 1 other locations)
Trial IDNCT06227611 on ClinicalTrials.gov

What this trial studies

This study aims to assess the effectiveness of three different perimetric grids in identifying central visual field defects in patients with early-stage glaucoma who have reduced ganglion cell layer thickness. By comparing the agreement between these grids, the research seeks to determine the most reliable method for detecting visual impairments associated with glaucoma. The observational nature of the study allows for the collection of data without any interventions, focusing solely on the evaluation of existing diagnostic techniques.

Who should consider this trial

Good fit: Ideal candidates for this study are glaucoma patients with a detectable optic nerve head defect and reduced ganglion cell layer thickness.

Not a fit: Patients under 18 years old, those with advanced glaucoma, or individuals with other eye conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the accuracy of glaucoma diagnosis and monitoring, leading to better patient outcomes.

How similar studies have performed: While similar studies have explored visual field testing in glaucoma, the specific comparison of these three perimetric grids in early glaucoma is a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* glaucoma patients with glaucomatous optic nerve head defect and reduced ganglion cell layer thickness

Exclusion Criteria:

* age\<18 years
* unable to read, understand and sign the written informed consent
* unable to perform visual field test
* advanced glaucoma with C/D\>0.7
* other causes of optic neuropathies
* retinal or macular diseases
* lens or corneal opacities
* spherical refractive defect \>± 6D
* cylindric refractive defect \>± 3D

Where this trial is running

Rome and 1 other locations

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Glaucoma
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.