Clinical trial Recruiting at 2 sites Observational Ages 18 and up

Evaluating visual field detection methods in early glaucoma patients

Official title: Evaluation of Different Perimetric Grids to Detect Central Visual Field Defect in Glaucoma Patients With Reduce Ganglion Cell Layer Thickness Measured by Spectral Domain OCT.

Run by Fondazione G.B. Bietti, IRCCS · NCT06227611 · Data updated 2026-11-12

This study is testing which of three different methods works best to find vision problems in people with early glaucoma.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment16 (estimated)
SponsorFondazione G.B. Bietti, IRCCS
Academic / other
Locations2 sites (Rome and 1 other locations)
StatusRecruiting
StartedMay 4, 2021
Main results expectedMay 4, 2022
Study endsMay 4, 2029
Registry record updatedSeptember 3, 2026
Trial IDNCT06227611 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are glaucoma patients with a detectable optic nerve head defect and reduced ganglion cell layer thickness.

Probably not a fit

Patients under 18 years old, those with advanced glaucoma, or individuals with other eye conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the effectiveness of three different perimetric grids in identifying central visual field defects in patients with early-stage glaucoma who have reduced ganglion cell layer thickness. By comparing the agreement between these grids, the research seeks to determine the most reliable method for detecting visual impairments associated with glaucoma. The observational nature of the study allows for the collection of data without any interventions, focusing solely on the evaluation of existing diagnostic techniques.

Why it matters

Potential benefit: If successful, this study could enhance the accuracy of glaucoma diagnosis and monitoring, leading to better patient outcomes.

How similar studies have gone: While similar studies have explored visual field testing in glaucoma, the specific comparison of these three perimetric grids in early glaucoma is a novel approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* glaucoma patients with glaucomatous optic nerve head defect and reduced ganglion cell layer thickness

Exclusion Criteria:

* age\<18 years
* unable to read, understand and sign the written informed consent
* unable to perform visual field test
* advanced glaucoma with C/D\>0.7
* other causes of optic neuropathies
* retinal or macular diseases
* lens or corneal opacities
* spherical refractive defect \>± 6D
* cylindric refractive defect \>± 3D

Where it's running

  • IRCCS-Fondazione GB Bietti
    Rome, Italy
    Recruiting
  • University of Rome Tor Vergata
    Rome, Italy
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.